Eur J Nucl Med Mol Imaging (2017) 44:1692–1694 DOI 10.1007/s00259-017-3757-6 EDITORIAL COMMENTARY SPECT/CT and PET/CT molecular imaging in medullary thyroid carcinoma. Are we running in the right direction? 1 2 1 Anna Margherita Maffione & Francesco Giammarile & Domenico Rubello Received: 6 June 2017 /Accepted: 7 June 2017 /Published online: 22 June 2017 Springer-Verlag GmbH Germany 2017 We have read with interest the paper by Yamaga LYI et al. Recurrent disease may be disclosed during follow-up of entitled B Ga-DOTATATE PET/CT in recurrent medullary MTC patients with persistently elevated/increasing serum Ct thyroid carcinoma: a lesion-by-lesion comparison with In- levels or, more rarely and especially in the case of poorly octreotide SPECT/CT and conventional imaging^ published differentiated and aggressive tumors, with increasing serum in the European Journal of Nuclear Medicine and Molecular carcinoembryonic antigen (CEA) levels. In general, scientific Imaging . It is focused on the comparison between different communities agree that an increase in the serum Ct level diagnostic imaging methods in order to investigate their effec- above 150 pg/mL should prompt additional imaging in order tiveness in localizing recurrent medullary thyroid carcinoma to localize and possibly surgically remove lesions. (MTC). Several parameters have probably biased the above Immunohistochemical
European Journal of Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Jun 22, 2017
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