Specifics of anaphase chromatid segregation in Drosophila melanogaster mitotic mutants

Specifics of anaphase chromatid segregation in Drosophila melanogaster mitotic mutants Anaphase chromatid segregation defects (CSDs) were quantitatively and qualitatively studied in neural ganglion cells of third-instar larvae of several control wild type Drosophila melanogaster strains and four strains with mutations of the aar v158 , ff3, mast v40 , and CycB 2g cell cycle genes. A linear specificity was observed for the CSD frequency, type, determination, and correction probability. The probability of anaphase CSD correction was close to unity in the control strains and lower in the mutant strains. The lower correction probability in the mutant strains was explained in the context of two findings, that the mutations induced the CSDs that were atypical of the wild type strains and were potentially uncorrectable in anaphase and that the mutations negatively affected the relative anaphase time in mitosis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Genetics Springer Journals

Specifics of anaphase chromatid segregation in Drosophila melanogaster mitotic mutants

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SP MAIK Nauka/Interperiodica
Copyright © 2008 by MAIK Nauka
Biomedicine; Microbial Genetics and Genomics; Animal Genetics and Genomics; Human Genetics
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