Some molecular aspects of the radiation-induced oxidative degradation of glutathione

Some molecular aspects of the radiation-induced oxidative degradation of glutathione Glutathione (GSH) is well known to have an important role as natural antioxidant. Some aspects of GSH degradation following the capture of water primary radicals in aerated or deaerated medium were investigated after γ-irradiation and by pulse radiolysis.___TAGSTART___BR___TAGEND___ Some relevant reactions involved in the GSH oxidation mechanism, leading to GSOO•-related products, were evidenced by pulse radiolysis experiments.___TAGSTART___BR___TAGEND___ From the quantitative determinations of the GSH degradation and the GSSG formation, useful indications on the fate of thiyl radicals (GS•), the most preminent sulfur centred intermediates, were drawn out in anaerobic and aerobic conditions. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Some molecular aspects of the radiation-induced oxidative degradation of glutathione

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Publisher
Brill Academic Publishers
Copyright
Copyright © 2002 by VSP 2002
Subject
Chemistry; Inorganic Chemistry; Physical Chemistry; Catalysis
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1163/156856702760129519
Publisher site
See Article on Publisher Site

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