Sleep Abnormalities in MultipleSystem Atrophy

Sleep Abnormalities in MultipleSystem Atrophy Purpose of review The purpose of this review was to explore the different sleep disorders associated with MSA, their mechanisms, and their treatments. Recent findings Stridor is a red flag for the diagnosis of MSA. Recent findings show that its presence in early stage of the disease is associated with a reduction in life expectancy. Its management should be fast and adapted. Its treatment with continuous positive airway pressure or tracheostomy is efficacious. Summary Sleep disorders in MSA are frequent and severe combining insomnia, daytime sleepiness, restless legs syndrome (RLS), REM sleep behavior disorder (RBD), and sleep disordered breathing (SDB). Sleep recordings confirm these disor- ders. Mechanisms involved in these disorders are complex associating (a) lesions of the pathways regulating sleep and wake or mood but also controlling movement, (b) iatrogenic effects of the treatments, and (3) consequences of the motor or dysautonomic symptoms. RBD prevalence is very high at the beginning of the motor symptoms but then seems to disappear. Introduction Multiple system atrophy (MSA) is a rapidly progressive dysfunction with gait or limb ataxia, dysarthria, or adult onset, neurodegenerative disorder, characterized gaze-evoked nystagmus, (b) parkinsonism with poor by an autonomic dysfunction such as orthostatic hypo- levodopa responsiveness http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Current Treatment Options in Neurology Springer Journals

Sleep Abnormalities in MultipleSystem Atrophy

Loading next page...
 
/lp/springer_journal/sleep-abnormalities-in-multiplesystem-atrophy-g7lNmwcU7e
Publisher
Springer US
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Neurology; Intensive / Critical Care Medicine; Internal Medicine; Ophthalmology; General Practice / Family Medicine; Diabetes
ISSN
1092-8480
eISSN
1534-3138
D.O.I.
10.1007/s11940-018-0503-8
Publisher site
See Article on Publisher Site

Abstract

Purpose of review The purpose of this review was to explore the different sleep disorders associated with MSA, their mechanisms, and their treatments. Recent findings Stridor is a red flag for the diagnosis of MSA. Recent findings show that its presence in early stage of the disease is associated with a reduction in life expectancy. Its management should be fast and adapted. Its treatment with continuous positive airway pressure or tracheostomy is efficacious. Summary Sleep disorders in MSA are frequent and severe combining insomnia, daytime sleepiness, restless legs syndrome (RLS), REM sleep behavior disorder (RBD), and sleep disordered breathing (SDB). Sleep recordings confirm these disor- ders. Mechanisms involved in these disorders are complex associating (a) lesions of the pathways regulating sleep and wake or mood but also controlling movement, (b) iatrogenic effects of the treatments, and (3) consequences of the motor or dysautonomic symptoms. RBD prevalence is very high at the beginning of the motor symptoms but then seems to disappear. Introduction Multiple system atrophy (MSA) is a rapidly progressive dysfunction with gait or limb ataxia, dysarthria, or adult onset, neurodegenerative disorder, characterized gaze-evoked nystagmus, (b) parkinsonism with poor by an autonomic dysfunction such as orthostatic hypo- levodopa responsiveness

Journal

Current Treatment Options in NeurologySpringer Journals

Published: Apr 20, 2018

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off