Skin barrier and microbiome in acne

Skin barrier and microbiome in acne Acne is an immune-mediated chronic inflammatory disease. Although several factors are involved in its pathophysiology, this process is not completely understood. Androgen hormone activity increases sebum production inside the pilosebaceous follicle, adjusting the environment for the development of Propionibacterium acnes which triggers inflammation. Knowing how others factors such as the skin barrier and microbiome are involved in acne, can help in understanding more about the disease and may help to conduct a better treatment. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Dermatological Research Springer Journals

Skin barrier and microbiome in acne

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag GmbH Germany, part of Springer Nature
Subject
Medicine & Public Health; Dermatology
ISSN
0340-3696
eISSN
1432-069X
D.O.I.
10.1007/s00403-017-1795-3
Publisher site
See Article on Publisher Site

Abstract

Acne is an immune-mediated chronic inflammatory disease. Although several factors are involved in its pathophysiology, this process is not completely understood. Androgen hormone activity increases sebum production inside the pilosebaceous follicle, adjusting the environment for the development of Propionibacterium acnes which triggers inflammation. Knowing how others factors such as the skin barrier and microbiome are involved in acne, can help in understanding more about the disease and may help to conduct a better treatment.

Journal

Archives of Dermatological ResearchSpringer Journals

Published: Nov 17, 2017

References

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