J Radiat Oncol (2017) 6:301–305 DOI 10.1007/s13566-017-0308-5 ORIGINAL RESEARCH Single-fraction radiation therapy provides highly effective palliation for cutaneous T cell lymphoma 1 2 2 1 Ankit Modh & Chauncey A. McHargue & Henry W. Lim & Farzan Siddiqui Received: 29 December 2016 /Accepted: 19 April 2017 /Published online: 25 April 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract after completion of TSET. CR was achieved in all these resid- Purpose/objective(s) We report our experience with single- ual lesions with an additional single-fraction dose of 8 Gy. No fraction radiation therapy in treating limited extent CTCL le- treatment-related toxicity was observed in any of the patients. sions for palliation. Conclusion Single-fraction radiation therapy is a highly effec- Materials/methods We reviewed 65 lesions in 18 patients tive palliative approach for treating limited extent CTCL le- with stage IA–IIB CTCL treated with a single fraction at our sions with minimal toxicity. institution from December 2014 to April 2016. Fifteen pa- tients had mycosis fungoides; all others (three) had primary Keywords Cutaneous Tcell lymphoma Mycosis . . cutaneous anaplastic large cell lymphoma. Clinical response Fungoides Radiation therapy Palliation to treatment was defined as complete response (CR, 90–100% reduction), partial response (PR, >50% but <90%), and
Journal of Radiation Oncology – Springer Journals
Published: Apr 25, 2017
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