Mammalian Genome 9, Brief Data Reports 179 Somatic cell hybrid analysis was performed with a well- this may play an important role in lymphoid tumorigenesis [6,7]. The IGL @ locus is known to be involved in the t(8;22) chromo- characterized panel of 38 hamster—bovine hybrid clones . some translocation in a variant form of Burkitt's lymphoma in Database deposit information: GenBank accession number: which the c-MYC gene is juxtaposed to the upstream region of CA L27833 . gene segment of the IGL @, thereby activating the oncogene . PCR primer sequences: Forward: 5' - TTTCTCTCTGTCCCCA- Furthermore, the locus is involved in a case of the t(3;22) chro- CTGC-3' (SINE region). Reverse: 5'-AGCCTTTCCTCCA- mosome translocation in B-cell non-Hodgkins lymphoma in which CTTCACC-3'. the BCL6 gene is translocated to the JX2 gene segment, causing Method of detection: The GenBank and EMBL database were promotor substitution . Thus, it is of interest to investigate searched for sequences homologous to several Bos taurus SINEs whether any particular chromosome translocations involve Ig light (Short Interspersed Nuclear Elements). The 5' flanking sequence chain genes in cat lymphomas and leukemias because the cat is of the bovine pregnancy-associated glycoprotein I gene showed being used as a
Mammalian Genome – Springer Journals
Published: Mar 28, 2009
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