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Y. Gao, Y. Song, Y. Yang, W. Liu, J. Tang (1979)
[Pharmacology of tanshinone (author's transl)].Yao xue xue bao = Acta pharmaceutica Sinica, 14 2
Zhisheng Xie, Thanh Truong, Pei Zhang, Fengguo Xu, Xiaojun Xu, Ping Li (2015)
Dan-Qi prescription ameliorates insulin resistance through overall corrective regulation of glucose and fat metabolism.Journal of ethnopharmacology, 172
R. Lin, Weirong Wang, Jun-tian Liu, Guangde Yang, Chun-jie Han (2006)
Protective effect of tanshinone IIA on human umbilical vein endothelial cell injured by hydrogen peroxide and its mechanism.Journal of ethnopharmacology, 108 2
Chunyong He, Jia Li, Niu-sheng Xu, Rufeng Wang, Zeyun Li, Li Yang, Zhengtao Wang (2015)
Pharmacokinetics, bioavailability, and metabolism of Notoginsenoside Fc in rats by liquid chromatography/electrospray ionization tandem mass spectrometry.Journal of pharmaceutical and biomedical analysis, 109
Qing-xi Yue, Fu-Bo Xie, Xiaowei Song, Wan-ying Wu, B. Jiang, S. Guan, Min Yang, Xuan Liu, D. Guo (2012)
Proteomic studies on protective effects of salvianolic acids, notoginsengnosides and combination of salvianolic acids and notoginsengnosides against cardiac ischemic-reperfusion injury.Journal of ethnopharmacology, 141 2
Min Song, Si-yun Zhang, Xiao-yue Xu, T. Hang, L. Jia (2010)
Simultaneous determination of three Panax notoginseng saponins at sub-nanograms by LC-MS/MS in dog plasma for pharmacokinetics of compound Danshen tablets.Journal of chromatography. B, Analytical technologies in the biomedical and life sciences, 878 32
Jingwei Zhang, F. Zhou, Xiaolan Wu, Yi Gu, Hua Ai, Yuan-ting Zheng, Yannan Li, Xiaoxuan Zhang, Gang Hao, Jianguo Sun, Ying Peng, Guangji Wang (2010)
20(S)-Ginsenoside Rh2 Noncompetitively Inhibits P-Glycoprotein In Vitro and In Vivo: A Case for Herb-Drug InteractionsDrug Metabolism and Disposition, 38
Chong-Zhi Wang, E. McEntee, S. Wicks, Ji-an Wu, C. Yuan (2006)
Phytochemical and analytical studies of Panax notoginseng (Burk.) F.H. ChenJournal of Natural Medicines, 60
A. Elsharkawy, F. Oakley, D. Mann (2005)
The role and regulation of hepatic stellate cell apoptosis in reversal of liver fibrosisApoptosis, 10
Hong Wang, Xiumei Gao, Bo-li Zhang (2005)
Tanshinone: an inhibitor of proliferation of vascular smooth muscle cells.Journal of ethnopharmacology, 99 1
Yong-guo Li, Long Song, Mei Liu, Zhi-bi Hu, Zheng-Tao Wang (2009)
Advancement in analysis of Salviae miltiorrhizae Radix et Rhizoma (Danshen).Journal of chromatography. A, 1216 11
Bai Xiao-ju (2012)
Suggestion on Selection of Chinese Patent Medicine Lists Recorded in Pharmacopoeia of People's Republic of China Volume I(2015 Version)Chinese Journal of Experimental Traditional Medical Formulae
Houfu Liu, Jun-ling Yang, Fei-fei Du, Xiumei Gao, Xutao Ma, Yuhong Huang, Fang Xu, Wei Niu, Feng-qing Wang, Yu Mao, Yan Sun, Tong Lu, Changxiao Liu, Bo-fan Zhang, Chuan Li (2009)
Absorption and Disposition of Ginsenosides after Oral Administration of Panax notoginseng Extract to RatsDrug Metabolism and Disposition, 37
T. Xue, Rustum Roy (2003)
Studying Traditional Chinese MedicineScience, 300
Chromatographia (2017) 80:1361–1369 DOI 10.1007/s10337-017-3365-4 ORIGINAL Simultaneous Determination of Seven Components in Human Plasma by LC–ESI–MS/MS After Oral Administration of Danqi Tablets with Application to a Pharmacokinetic Study 1 1 Jiawei Shen · Xiuqin Cao Received: 24 April 2017 / Revised: 14 July 2017 / Accepted: 18 July 2017 / Published online: 31 July 2017 © Springer-Verlag GmbH Germany 2017 Abstract A rapid and sensitive LC/MS/MS method has of Danqi tablets, which, in turn, aid in explaining the mech- been developed and validated for simultaneous determina- anism of its effectiveness and toxicity. tion of GRg1, GRb1, NGR1, tanshinone IIA, salvianolic acid B, dihydrotanshinone I, and danshensu in human Keywords LC/MS/MS · Danqi tablets · plasma after oral administration. The plasma samples were Pharmacokinetics · Human pretreated by protein precipitation with acetone–acetoni- trile–HCl (20:75:5, v/v/v). Separations were performed on a ACQUITY UPLC HSST3 column (50 mm × 2.1 mm, Introduction i.d., 1.8 μm) with gradient elution using 0.1% formic acid in water and 0.1% formic acid in a mixture of methanol/ Herbal medicines (HMs) have been an essential of the −1 acetonitrile (v:v; 1:1), at a flow rate of 0.3 mL min . The health care system in Asian countries and have been widely method was linear over the tested concentration ranges used
Chromatographia – Springer Journals
Published: Jul 31, 2017
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