Silica sulfuric acid-catalyzed Claisen-Schmidt condensation of 1,3,4 trisubstituted pyrrole 2,5 dione to chalcones

Silica sulfuric acid-catalyzed Claisen-Schmidt condensation of 1,3,4 trisubstituted pyrrole 2,5... A series of 11 chalcones was synthesized from 1-(4-acetylphenyl)-3,4-dibromo-1H-pyrrole-2,5-dione with various substituted benzaldehyde under solvent-free conditions using silica-sulphuric acid as a catalyst. The yields of chalcones are more than 90 %. All the compounds were characterized by physical, spectroscopic, and elemental analysis. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Silica sulfuric acid-catalyzed Claisen-Schmidt condensation of 1,3,4 trisubstituted pyrrole 2,5 dione to chalcones

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Publisher
Springer Netherlands
Copyright
Copyright © 2012 by Springer Science+Business Media B.V.
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-012-0553-6
Publisher site
See Article on Publisher Site

Abstract

A series of 11 chalcones was synthesized from 1-(4-acetylphenyl)-3,4-dibromo-1H-pyrrole-2,5-dione with various substituted benzaldehyde under solvent-free conditions using silica-sulphuric acid as a catalyst. The yields of chalcones are more than 90 %. All the compounds were characterized by physical, spectroscopic, and elemental analysis.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Apr 25, 2012

References

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