Electronic supplementary material The online version of this article (doi:10.1007/s11164-016-2667-8) contains supplementary material, which is available to authorized users. & Murlidhar S. Shingare email@example.com Bhaskar R. Sathe firstname.lastname@example.org Department of Chemistry, Dr. Babasaheb Ambedkar Marathwada University, Aurangabad 431004, India 123 830 P. V. Shitre et al. Keywords SiO nanospheres Graphene oxide (GO) SiO –GO nanohybrid 2 2 Functionalized quinoxaline Cyclocondensation reaction Introduction Heterocyclic compounds have attracted considerable attention because of their ample biological activities and other pharmaceutical contributions. Interestingly, a variety of six-membered heterocycles with two nitrogen-containing heteroatoms have received meticulous attention recently. Likewise, quinoxaline derivatives have acquired tremendous scope due to their tunable and varied biological and pharmaceutical applications, especially for anti-bacterial , anti-cancer , anti- viral , anti-HIV , and kinase inhibition . Moreover, they are also active ingredients of several anti-tumor agents such as chloroquinoxaline sulfonamide (CQS), NCGS5879-01 , and XK469 that are known to be effective by targeting different pathways leading to cancer. Furthermore, varenicline is used for treating nicotine addiction, and brimonidine is used for treating glaucoma [7, 8]. Apart from its medicinal signiﬁcance, this scaffold ﬁnds wider technical applications in dye industries , efﬁcient electron luminescent materials , organic semiconductors
Research on Chemical Intermediates – Springer Journals
Published: Jul 27, 2016
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