Reactions 1680, p306 - 2 Dec 2017
Diminished smell and taste: case report
A 52-year-old woman developed diminished smell and taste
while receiving sertraline.
The woman, who had a history of depression, started
receiving sertraline 50 mg/day [route not stated]. Two weeks
later, her taste dropped from 80% to 20%, with chocolate taste
dropping from 60% of normal to 10% of normal, eggroll and
fried rice from 100% of normal taste to 50 and 0% respectively.
Her taste of coffee dropped from 75% to 50% and blue
raspberry sucker from 150% to 75%. Prior to sertraline
administration, she had five olfactory windows a day, but post-
sertraline, she had zero. The quick smell identification test and
alcohol sniff test revealed anosmia. Also, the retronasal smell
index showed abnormal results. She previously had received
citalopram and showed loss in smell and taste.
Sertraline was discontinued and the woman’s taste and
smell partially returned.
The woman’s smell and taste reduced after restarting the
sertraline therapy [outcomes not stated].
Author comment: "In this patient impairment of smell
and taste occurred on sertraline. There was an improvement
when it was discontinued. This temporal relationship suggests
that sertraline is the pathologic factor for smell and taste
impairment in this individual."
Elazzab A, et al. Sertraline-induced chemosensory dysfunction. CNS Spectrums
22: 62 abstr. 101, No. 1, Feb 2017. Available from: URL: http://doi.org/10.1017/
S1092852916000900 [abstract] - Egypt
Reactions 2 Dec 2017 No. 16800114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved