Sertraline Reactions 1680, p306 - 2 Dec 2017 Diminished smell and taste: case report A 52-year-old woman developed diminished smell and taste while receiving sertraline. The woman, who had a history of depression, started receiving sertraline 50 mg/day [route not stated]. Two weeks later, her taste dropped from 80% to 20%, with chocolate taste dropping from 60% of normal to 10% of normal, eggroll and fried rice from 100% of normal taste to 50 and 0% respectively. Her taste of coffee dropped from 75% to 50% and blue raspberry sucker from 150% to 75%. Prior to sertraline administration, she had five olfactory windows a day, but post- sertraline, she had zero. The quick smell identification test and alcohol sniff test revealed anosmia. Also, the retronasal smell index showed abnormal results. She previously had received citalopram and showed loss in smell and taste. Sertraline was discontinued and the woman’s taste and smell partially returned. The woman’s smell and taste reduced after restarting the sertraline therapy [outcomes not stated]. Author comment: "In this patient impairment of smell and taste occurred on sertraline. There was an improvement when it was discontinued. This temporal relationship suggests that sertraline is the pathologic factor for smell and taste impairment in this individual." Elazzab A, et al. Sertraline-induced chemosensory dysfunction. CNS Spectrums 22: 62 abstr. 101, No. 1, Feb 2017. Available from: URL: S1092852916000900 [abstract] - Egypt 803285024 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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