Serotonergic medications, herbal supplements, and perioperative serotonin syndrome

Serotonergic medications, herbal supplements, and perioperative serotonin syndrome Can J Anesth/J Can Anesth (2017) 64:940–946 DOI 10.1007/s12630-017-0918-9 CASE REP O RTS / CAS E SERIES Serotonergic medications, herbal supplements, and perioperative serotonin syndrome ´ ´ ´ ` Medicaments serotoninergiques, supplements a base de plantes ´ ´ ´ ´ medicinales et syndrome serotoninergique perioperatoire . . . Mary E. Warner, MD Julian Naranjo, DO Emily M. Pollard, MD . . Toby N. Weingarten, MD Mark A. Warner, MD Juraj Sprung, MD, PhD Received: 9 March 2017 / Revised: 10 April 2017 / Accepted: 16 June 2017 / Published online: 30 June 2017 Canadian Anesthesiologists’ Society 2017 Abstract highlights that taking serotonergic agents concomitantly Purpose Perioperative use of serotonergic agents can produce the compounding effect that causes serotonin increases the risk of serotonin syndrome. We describe the syndrome. The delayed presentation of serotonin syndrome occurrence of serotonin syndrome after fentanyl use in two in the patient who received a large dose of midazolam patients taking multiple serotonergic agents. suggests that outpatients taking multiple serotonergic Clinical features Two patients who had been taking drugs who receive benzodiazepines may require longer multiple serotonergic medications or herbal supplements postprocedural monitoring. (one patient taking fluoxetine, turmeric supplement, and acyclovir; the other taking fluoxetine Canadian Journal of Anesthesia/Journal canadien d'anesthésie Springer Journals

Serotonergic medications, herbal supplements, and perioperative serotonin syndrome

Loading next page...
Springer US
Copyright © 2017 by Canadian Anesthesiologists' Society
Medicine & Public Health; Anesthesiology; Pain Medicine; Intensive / Critical Care Medicine; Pneumology/Respiratory System; Cardiology; Pediatrics
Publisher site
See Article on Publisher Site


You’re reading a free preview. Subscribe to read the entire article.

DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches


Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.



billed annually
Start Free Trial

14-day Free Trial