Arch Virol (2000) 145: 1029–1033
Serological evidence of adenovirus infection in cats
, J. Farkas
, É. Adám
, O. Dobay
, Cs. Jeney
, I. Nász
, and J. Ongrádi
University of Veterinary Sciences, Budapest, Hungary
Institute of Microbiology, Semmelweis Medical University, Budapest, Hungary
Lakat-Vet BT, Budapest, Hungary
Accepted January 4, 2000
Summary. The widespread presence of adenoviruses in various species makes
it probable that infection and the carrier state also exist in cats. On the basis of
these considerations, investigations were carried out to ﬁnd antibodies against
adenovirus in sera from different cat populations kept under different conditions.
For the antibody detection, puriﬁed adenovirus was used in an indirect ELISA.
To produce positive serum, SPF cats were immunized with a puriﬁed hexon
preparation. Altogether 632 ﬁeld sera of different origin were tested. Among
ﬁeld samples, adenovirus seropositivity varied between 10–26%.
Since the ﬁrst isolation of adenoviruses [16, 29] about 130 serotypes have been
described from different mammalian and avian species [11, 28, 30]. The presence
of adenoviruses has been veriﬁed by histopathology and electron microscopy 
in poikilothermic species, such as amphibians , reptiles , and even in ﬁsh
. Adenoviruses are grouped in two genera on the basis of their origin. The
Mastadenovirusgenus includes serotypesisolated fromhumans andmammalians,
while adenoviruses coming from birds belong to the Aviadenovirus genus .
Occurrence of mastadenoviruses has been veriﬁed by isolation and characteri-
zation in 9 mammalian species apart from humans . The actual number of
adenoviruses in a given species depends more on the effort made to obtain isolates
than on the frequency of occurrence . Grouping of adenoviruses of animal
origin is generally done after the host species, e.g., simian, canine, bovine, ovine,
rabbit, and so on [1, 4, 6, 8–10, 22].
Since the host spectrum of individual adenovirus species is rather narrow ,
a genuine adenovirus of cats may be expected. Adenoviruses have yet to be iso-
lated from cats or other felidae, although their presence had been demonstrated