Eur J Plast Surg (2016) 39:235–236 DOI 10.1007/s00238-015-1119-9 LETTER TO THE EDITOR Sequelae of radiotherapy-induced coronary artery disease in breast reconstruction 1 1 1 Hazim Sadideen & Korina Theodoraki & Sunil S. Thomas Received: 3 May 2015 /Accepted: 5 June 2015 /Published online: 19 June 2015 Springer-Verlag Berlin Heidelberg 2015 Sir, free. Seven years after completion of radiotherapy, she pre- Approximately 37 % of breast cancer patients who undergo sented to the emergency department with syncopal episodes breast conserving surgery or are found to have positive lymph and a four week history of exertional angina. Although she nodes receive adjuvant radiotherapy . Known side-effects thought this pain was implant-related, her blood results showed a positive troponin (peak of 75 ng/L) and ECG’s of radiotherapy include wound breakdown, scarring, and radiation-induced angiosarcoma . Less commonly cardio- showed T wave inversion in all the anterior leads, indicating vascular complications can occur secondary to unwanted in- an acute myocardial infarction. Coronary angiogram re- direct irradiation of the heart, including coronary artery dis- vealed critical coronary disease involving the left anterior ease, pericarditis, and cardiomyopathy . Chemotherapy for descending, left circumflex and right coronary arteries (i.e. breast cancer can also induce cardiotoxicity, mainly
European Journal of Plastic Surgery – Springer Journals
Published: Jun 1, 2016
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