Sensitivity of Nasal Bone as Aneuploidy Marker—First Trimester versus Second Trimester Assessment

Sensitivity of Nasal Bone as Aneuploidy Marker—First Trimester versus Second Trimester Assessment J. Fetal Med. (September 2017) 4:109–117 DOI 10.1007/s40556-017-0128-0 ORIGINAL ARTICLE Sensitivity of Nasal Bone as Aneuploidy Marker—First Trimester versus Second Trimester Assessment 1 1 1 • • Selvaraj Ravi Lakshmy Umapathy Shobana Nity Rose Received: 25 March 2017 / Accepted: 1 July 2017 / Published online: 20 July 2017 Society of Fetal Medicine 2017 Abstract Inclusion in the second trimester would still have the same Objective To assess the reliability of nasal bone (NB) as detection rate but would eliminate technical difficulties of an aneuploidy marker in the first trimester vs. second tri- imaging NB in the first trimester. mester and to highlight the technical difficulties in evalu- ating the nasal bone at 11–14 week scan. Keywords Nasal bone  Aneuploidy  Retronasal triangle Methods Nasal bone was examined in 4478 women who Midsagittal plane  Equal sign  First trimester screening enrolled for nuchal translucency (NT) scan and NB was Nuchal translucency  Non-invasive prenatal testing assessed in both midsagittal and coronal planes. Risk assessment was done based on serum biochemistry and NT Abbreviations without including the NB status. Absence of NB was NT Nuchal translucency confirmed at 17 week and aneuploidy risk was modified b-HCG Beta human http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Fetal Medicine Springer Journals

Sensitivity of Nasal Bone as Aneuploidy Marker—First Trimester versus Second Trimester Assessment

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Publisher
Springer India
Copyright
Copyright © 2017 by Society of Fetal Medicine
Subject
Medicine & Public Health; Maternal and Child Health; Diagnostic Radiology; Ultrasound; Obstetrics/Perinatology; Reproductive Medicine
ISSN
2348-1153
eISSN
2348-8859
D.O.I.
10.1007/s40556-017-0128-0
Publisher site
See Article on Publisher Site

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