J. Fetal Med. (September 2017) 4:109–117 DOI 10.1007/s40556-017-0128-0 ORIGINAL ARTICLE Sensitivity of Nasal Bone as Aneuploidy Marker—First Trimester versus Second Trimester Assessment 1 1 1 • • Selvaraj Ravi Lakshmy Umapathy Shobana Nity Rose Received: 25 March 2017 / Accepted: 1 July 2017 / Published online: 20 July 2017 Society of Fetal Medicine 2017 Abstract Inclusion in the second trimester would still have the same Objective To assess the reliability of nasal bone (NB) as detection rate but would eliminate technical difﬁculties of an aneuploidy marker in the ﬁrst trimester vs. second tri- imaging NB in the ﬁrst trimester. mester and to highlight the technical difﬁculties in evalu- ating the nasal bone at 11–14 week scan. Keywords Nasal bone Aneuploidy Retronasal triangle Methods Nasal bone was examined in 4478 women who Midsagittal plane Equal sign First trimester screening enrolled for nuchal translucency (NT) scan and NB was Nuchal translucency Non-invasive prenatal testing assessed in both midsagittal and coronal planes. Risk assessment was done based on serum biochemistry and NT Abbreviations without including the NB status. Absence of NB was NT Nuchal translucency conﬁrmed at 17 week and aneuploidy risk was modiﬁed b-HCG Beta human
Journal of Fetal Medicine – Springer Journals
Published: Jul 20, 2017
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