SEN virus detection in thalassemic patients infected with hepatitis C virus

SEN virus detection in thalassemic patients infected with hepatitis C virus HCV infection is known to be associated with clinical complications in thalassemic patients. D and H genotypes of SEN virus (SENV) are associated with blood-product transfusion and possibly non-A-to-E hepatitis. In this study, SENV viremia and its effect on liver ALT level in thalassemic patients, thalassemic patients infected with HCV, and HCV-infected patients were examined. Semi-nested PCR was conducted for detection of genotype H and D DNA, and the level of alanine aminotransferase (ALT) was measured. There was no significant difference in the mean ALT level in the studied groups and between SENV-positive and SENV-negative individuals. The results also showed that SENV infection does not affect the ALT level in these patients. Archives of Virology Springer Journals

SEN virus detection in thalassemic patients infected with hepatitis C virus

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Springer Vienna
Copyright © 2012 by Springer-Verlag Wien
Biomedicine; Virology; Infectious Diseases; Medical Microbiology
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