Semi-quantitative analysis of salivary gland scintigraphy in Sjögren’s syndrome diagnosis: a first-line tool

Semi-quantitative analysis of salivary gland scintigraphy in Sjögren’s syndrome diagnosis: a... Objective The aim of this study was the assessment of semi- lower in pSS patients compared to those in non-pSS quantified salivary gland dynamic scintigraphy (SGdS) pa- (p < 0.001). ROC curve showed significantly large AUC for rameters independently and in an integrated way in order to both the parameters (p <0.05). predict primary Sjögren’s syndrome (pSS). Parotid UP and submandibular EF, assessed by Materials and methods Forty-six consecutive patients (41 fe- univariated and multivariate logistic regression, showed males; age 61 ± 11 years) with sicca syndrome were studied a significant and independent correlation with pSS diag- by SGdS after injection of 200 MBq of pertechnetate. In six- nosis (p value <0.05). No correlation was found between teen patients, pSS was diagnosed, according to American- SGdS semi-quantitative parameters and ESSDAI. The European Consensus Group criteria (AECGc). proposed nomogram accuracy was 87%. Semi-quantitative parameters (uptake (UP) and excretion Conclusion SGdS is an accurate and reproducible tool for the fraction (EF)) were obtained for each gland. ROC curves were diagnosis of pSS. ESSDAI was not shown to be correlated used to determine the best cut-off value. The area under the with SGdS data. Clinical relevance SGdS should be the first-line imaging http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical Oral Investigations Springer Journals

Semi-quantitative analysis of salivary gland scintigraphy in Sjögren’s syndrome diagnosis: a first-line tool

Loading next page...
 
/lp/springer_journal/semi-quantitative-analysis-of-salivary-gland-scintigraphy-in-sj-gren-s-ro9aL6u0fE
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Dentistry; Dentistry
ISSN
1432-6981
eISSN
1436-3771
D.O.I.
10.1007/s00784-016-2034-6
Publisher site
See Article on Publisher Site

Abstract

Objective The aim of this study was the assessment of semi- lower in pSS patients compared to those in non-pSS quantified salivary gland dynamic scintigraphy (SGdS) pa- (p < 0.001). ROC curve showed significantly large AUC for rameters independently and in an integrated way in order to both the parameters (p <0.05). predict primary Sjögren’s syndrome (pSS). Parotid UP and submandibular EF, assessed by Materials and methods Forty-six consecutive patients (41 fe- univariated and multivariate logistic regression, showed males; age 61 ± 11 years) with sicca syndrome were studied a significant and independent correlation with pSS diag- by SGdS after injection of 200 MBq of pertechnetate. In six- nosis (p value <0.05). No correlation was found between teen patients, pSS was diagnosed, according to American- SGdS semi-quantitative parameters and ESSDAI. The European Consensus Group criteria (AECGc). proposed nomogram accuracy was 87%. Semi-quantitative parameters (uptake (UP) and excretion Conclusion SGdS is an accurate and reproducible tool for the fraction (EF)) were obtained for each gland. ROC curves were diagnosis of pSS. ESSDAI was not shown to be correlated used to determine the best cut-off value. The area under the with SGdS data. Clinical relevance SGdS should be the first-line imaging

Journal

Clinical Oral InvestigationsSpringer Journals

Published: Jan 3, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off