Selegiline Reactions 1680, p305 - 2 Dec 2017 Mild skin irritation: case report An 84-year-old woman developed mild skin irritation following treatment with selegiline [Emsam] and haloperidol [Haldol]. The woman, who had depression, started to receive transdermal selegiline 6 mg/day. Later, topical haloperidol gel 0.5mg twice daily was added due to her agitation and aggressive behaviours. Following three weeks of selegiline therapy, her depressive symptoms improved; however, she experienced mild skin irritation, which eventually resolved [durations of treatments to reaction onset not stated]. Her resistive behaviours continued especially at night; therefore, haloperidol at bedtime was increased to 1mg. The depressive symptoms returned after 8 months. She was maintained on topical gels till she died of end-stage cardiac disease in February 2015. Author comment: "There were no side effects noted except for mild skin irritation that resolved." Patterson KT. Using transdermal administration of psychiatric medications to enhance quality of life in an elderly nursing home patient diagnosed with dementia and depression: A case study. CNS Spectrums 21: 108-109, No. 1, Feb 2016. Available from: URL: [abstract] - USA 803284897 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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