Secukinumab/ustekinumab

Secukinumab/ustekinumab Reactions 1680, p304 - 2 Dec 2017 Paradoxical psoriasis: 2 case reports In a monocentric retrospective observational study of five patients, a 37-year-old woman and a 46-year-old woman developed paradoxical psoriasis during treatment with ustekinumab (1 patient) or secukinumab (1 patient) [routes and outcomes not stated]. Patient 1: A 37-year-old woman, who was diagnosed with SAPHO syndrome characterised by palmoplantar pustulosis since three years, received treatment with ustekinumab 90mg. Subsequently, she developed paradoxical psoriasis. After six months of the treatment, ustekinumab was discontinued. Patient 2: A 46-year-old woman, who was diagnosed with SAPHO syndrome characterised by palmoplantar pustulosis since five years, received treatment with secukinumab 150mg. Subsequently, she developed paradoxical psoriasis. After three months of the treatment, secukinumab was discontinued. Author comment: "No particular safety concerns were reported, except cases of paradoxical psoriasis flare(contributing to discontinuation of treatment) in one under ustekinumab, and the other case under secukinumab." Wendling D, et al. IL-23/Th17 targeted therapies in SAPHO syndrome. A case series. Joint Bone Spine 84: 733-735, No. 6, Dec 2017. Available from: URL: https://doi.org/10.1016/j.jbspin.2017.05.016 - France 803284087 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Secukinumab/ustekinumab

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
Free
1 page

Loading next page...
1 Page
 
/lp/springer_journal/secukinumab-ustekinumab-a0i7JA5Koa
Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-39235-4
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p304 - 2 Dec 2017 Paradoxical psoriasis: 2 case reports In a monocentric retrospective observational study of five patients, a 37-year-old woman and a 46-year-old woman developed paradoxical psoriasis during treatment with ustekinumab (1 patient) or secukinumab (1 patient) [routes and outcomes not stated]. Patient 1: A 37-year-old woman, who was diagnosed with SAPHO syndrome characterised by palmoplantar pustulosis since three years, received treatment with ustekinumab 90mg. Subsequently, she developed paradoxical psoriasis. After six months of the treatment, ustekinumab was discontinued. Patient 2: A 46-year-old woman, who was diagnosed with SAPHO syndrome characterised by palmoplantar pustulosis since five years, received treatment with secukinumab 150mg. Subsequently, she developed paradoxical psoriasis. After three months of the treatment, secukinumab was discontinued. Author comment: "No particular safety concerns were reported, except cases of paradoxical psoriasis flare(contributing to discontinuation of treatment) in one under ustekinumab, and the other case under secukinumab." Wendling D, et al. IL-23/Th17 targeted therapies in SAPHO syndrome. A case series. Joint Bone Spine 84: 733-735, No. 6, Dec 2017. Available from: URL: https://doi.org/10.1016/j.jbspin.2017.05.016 - France 803284087 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off