Secukinumab

Secukinumab Reactions 1704, p339 - 2 Jun 2018 First report of cutaneous lichen planus: case report A 56-year-old man developed cutaneous lichen planus during treatment with secukinumab [dosage and route not stated] for chronic plaque psoriasis. The man had chronic plaque psoriasis. He presented with a 2 month history of violaceous and pruritic, thickened plaques on his bilateral lower limbs and buttocks during treatment with secukinumab for psoriasis. Initially, the plaques developed at his ankles and progressed gradually to proximally to his thighs and buttocks. The plaques demonstrated Wickham striae. Histology test revealed a band-like lymphocyte inflammatory infiltrate just beneath the epithelium with basal epithelial apoptoses. The man was started treated with betamethasone dipropionate which had moderate effect [time to reaction onset not stated]. Author comment: "We report the first case of drug- induced cutaneous [lichen planus] in the setting of secukinumab for treatment of chronic plaque psoriasis. " Doolan B, et al. Cutaneous lichen planus induced by secukinumab. Australasian Journal of Dermatology 59 (Suppl. 1): 60-61, May 2018. Available from: URL: http://doi.org/10.1111/ajd.17_12815 [abstract] - Australia 803323605 » Editorial comment: A search of AdisBase, Medline and Embase did not reveal any previous case reports of cutaneous lichen planus associated with secukinumab. The results from the WHO ADR database are pending. 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Secukinumab

Reactions Weekly , Volume 1704 (1) – Jun 2, 2018
Free
1 page
Loading next page...
1 Page
 
/lp/springer_journal/secukinumab-3tdVkMjFnD
Publisher
Springer International Publishing
Copyright
Copyright © 2018 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-018-46982-y
Publisher site
See Article on Publisher Site

Abstract

Reactions 1704, p339 - 2 Jun 2018 First report of cutaneous lichen planus: case report A 56-year-old man developed cutaneous lichen planus during treatment with secukinumab [dosage and route not stated] for chronic plaque psoriasis. The man had chronic plaque psoriasis. He presented with a 2 month history of violaceous and pruritic, thickened plaques on his bilateral lower limbs and buttocks during treatment with secukinumab for psoriasis. Initially, the plaques developed at his ankles and progressed gradually to proximally to his thighs and buttocks. The plaques demonstrated Wickham striae. Histology test revealed a band-like lymphocyte inflammatory infiltrate just beneath the epithelium with basal epithelial apoptoses. The man was started treated with betamethasone dipropionate which had moderate effect [time to reaction onset not stated]. Author comment: "We report the first case of drug- induced cutaneous [lichen planus] in the setting of secukinumab for treatment of chronic plaque psoriasis. " Doolan B, et al. Cutaneous lichen planus induced by secukinumab. Australasian Journal of Dermatology 59 (Suppl. 1): 60-61, May 2018. Available from: URL: http://doi.org/10.1111/ajd.17_12815 [abstract] - Australia 803323605 » Editorial comment: A search of AdisBase, Medline and Embase did not reveal any previous case reports of cutaneous lichen planus associated with secukinumab. The results from the WHO ADR database are pending. 0114-9954/18/1704-0001/$14.95 Adis © 2018 Springer International Publishing AG. All rights reserved Reactions 2 Jun 2018 No. 1704

Journal

Reactions WeeklySpringer Journals

Published: Jun 2, 2018

There are no references for this article.

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off