Seasonal distribution and epidemiological characteristics of human metapneumovirus infections in pediatric inpatients in Southeast China

Seasonal distribution and epidemiological characteristics of human metapneumovirus infections in... Human metapneumovirus (hMPV) is an important respiratory pathogen in young children whose seasonal activity varies substantially from year to year among different populations. This study was conducted to investigate if there was a seasonal variation in the incidence of hMPV infection in young children and possible associations between hMPV infection and local meteorological parameters in Suzhou, China. A total of 6,655 children with acute respiratory tract infection (ARTI) admitted to the Children’s Hospital affiliated to Soochow University, Suzhou, were tested from January 2006 to December 2009 for the presence of hMPV using reverse-transcription polymerase chain reaction. The relationship between the presence of the virus and regional meteorological conditions was analyzed by linear and multivariate regression analysis. The overall hMPV infection incidence over the four-year study was 8.2 %, 8.1 %, 12.7 % and 7.4 % per year, respectively. Four hundred eighty-eight hMPV-positive children (78.2 %) were younger than 3 years of age. hMPV infections appear to have a seasonal distribution in Suzhou. In 2006, 2007 and 2009, the peak seasons were in December to January, while in 2008, the peak of hMPV activity occurred in May. The incidence of hMPV infection was negatively correlated with the average monthly temperature and rainfall. hMPV was one of the most common viral pathogens after respiratory syncytial virus that was associated with acute respiratory tract infection in children in Suzhou. hMPV infection occurred throughout the year with peaks during late winter and early spring. Climatic factors, especially monthly average temperature, may affect the prevalence of hMPV in Suzhou. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Seasonal distribution and epidemiological characteristics of human metapneumovirus infections in pediatric inpatients in Southeast China

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Publisher
Springer Vienna
Copyright
Copyright © 2013 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-012-1492-7
Publisher site
See Article on Publisher Site

References

  • Acute lower respiratory tract infections by human metapneumovirus in children in Southwest China: a 2-year study
    Chen, X; Zhang, ZY; Zhao, Y; Liu, EM; Zhao, XD
  • Prevalence of human metapneumovirus in hospitalized children with respiratory tract infections in Tianjin
    Li, XY; Chen, JY; Kong, M; Su, X; Yi, YP; Zou, M
  • Human metapneumovirus infections–biannual epidemics and clinical findings in children in the region of Basel, Switzerland
    Heininger, U; Kruker, AT; Bonhoeffer, J; Schaad, UB

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