Chin J Integr Med 2018 Jun;24(6):429-435 • • Available online at link.springer.com/journal/11655 hinese Journal of Integrative Medicine Journal homepage: www.cjim.cn/zxyjhen/zxyjhen/ch/index.aspx E-mail: email@example.com Original Article Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model 1,2 3 1 1 XU Yang , CHEN Xiu-ping , ZHANG Feng , HOU Hua-hua , 1 1 1 ZHANG Jing-yi , LIN Shu-xian , and SUN An-sheng Objective Objective ABSTRACT ABSTRACT : : To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery balloon-injury balloon-injury model. model. Methods Methods: : The intimal hyperplasia model was established by rubbing the endothelia with a The intimal hyperplasia model was established by rubbing the endothelia with a balloon balloon catheter in the common carotid artery (CCA) of rats. Fifty rats were randomly divided into catheter in the common carotid artery (CCA) of rats. Fifty rats were randomly divided into ﬁ ﬁ ve ve groups, groups, iie. sham, model, Rut (25, 50 and 75 mg/kg) with 10 rats of each group. The rats were treated with or without e. sham, model, Rut (25, 50 and 75 mg/kg) with 10 rats
Chinese Journal of Integrative Medicine – Springer Journals
Published: Sep 1, 2017
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