Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model

Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model Chin J Integr Med 2018 Jun;24(6):429-435 • • Available online at link.springer.com/journal/11655 hinese Journal of Integrative Medicine Journal homepage: www.cjim.cn/zxyjhen/zxyjhen/ch/index.aspx E-mail: cjim_en@cjim.cn Original Article Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model 1,2 3 1 1 XU Yang , CHEN Xiu-ping , ZHANG Feng , HOU Hua-hua , 1 1 1 ZHANG Jing-yi , LIN Shu-xian , and SUN An-sheng Objective Objective ABSTRACT ABSTRACT : : To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery balloon-injury balloon-injury model. model. Methods Methods: : The intimal hyperplasia model was established by rubbing the endothelia with a The intimal hyperplasia model was established by rubbing the endothelia with a balloon balloon catheter in the common carotid artery (CCA) of rats. Fifty rats were randomly divided into catheter in the common carotid artery (CCA) of rats. Fifty rats were randomly divided into fi fi ve ve groups, groups, iie. sham, model, Rut (25, 50 and 75 mg/kg) with 10 rats of each group. The rats were treated with or without e. sham, model, Rut (25, 50 and 75 mg/kg) with 10 rats http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Chinese Journal of Integrative Medicine Springer Journals

Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model

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Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2018 by Chinese Association of the Integration of Traditional and Western Medicine
Subject
Medicine & Public Health; Medicine/Public Health, general
ISSN
1672-0415
eISSN
1993-0402
D.O.I.
10.1007/s11655-017-2900-3
Publisher site
See Article on Publisher Site

Abstract

Chin J Integr Med 2018 Jun;24(6):429-435 • • Available online at link.springer.com/journal/11655 hinese Journal of Integrative Medicine Journal homepage: www.cjim.cn/zxyjhen/zxyjhen/ch/index.aspx E-mail: cjim_en@cjim.cn Original Article Rutaecarpine Inhibits Intimal Hyperplasia in A Balloon-Injured Rat Artery Model 1,2 3 1 1 XU Yang , CHEN Xiu-ping , ZHANG Feng , HOU Hua-hua , 1 1 1 ZHANG Jing-yi , LIN Shu-xian , and SUN An-sheng Objective Objective ABSTRACT ABSTRACT : : To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery To investigate the effect and potential mechanisms of rutaecarpine (Rut) in a rat artery balloon-injury balloon-injury model. model. Methods Methods: : The intimal hyperplasia model was established by rubbing the endothelia with a The intimal hyperplasia model was established by rubbing the endothelia with a balloon balloon catheter in the common carotid artery (CCA) of rats. Fifty rats were randomly divided into catheter in the common carotid artery (CCA) of rats. Fifty rats were randomly divided into fi fi ve ve groups, groups, iie. sham, model, Rut (25, 50 and 75 mg/kg) with 10 rats of each group. The rats were treated with or without e. sham, model, Rut (25, 50 and 75 mg/kg) with 10 rats

Journal

Chinese Journal of Integrative MedicineSpringer Journals

Published: Sep 1, 2017

References

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