Rotavirus infection in children of Nizhny Novgorod, Russia: the gradual change of the virus allele from P(8)-1 to P(8)-3 in the period 1984–2010

Rotavirus infection in children of Nizhny Novgorod, Russia: the gradual change of the virus... A collection of rotavirus samples collected over a 26-year period was examined to study the dynamics of change in RV strains of genotype P(8) in a geographically defined population (Nizhny Novgorod, Russia; children under 6 years) with no vaccine pressure. Phylogenetic analysis of gene VP4 (subunit VP8*) showed the presence of two lines of genotype P(8): P(8)-1 and P(8)-3. Since 1997, the dominant population of rotavirus has been occupied by strains carrying the allele P(8)-3, which is associated with G1, G3 and G4. The complete replacement of the allele P(8)-1 to P(8)-3 took 19 epidemic years. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Rotavirus infection in children of Nizhny Novgorod, Russia: the gradual change of the virus allele from P(8)-1 to P(8)-3 in the period 1984–2010

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Publisher
Springer Vienna
Copyright
Copyright © 2012 by Springer-Verlag Wien
Subject
Biomedicine; Virology; Infectious Diseases; Medical Microbiology
ISSN
0304-8608
eISSN
1432-8798
D.O.I.
10.1007/s00705-012-1426-4
Publisher site
See Article on Publisher Site

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