Role of Apoptosis in Age-Related Pathologies

Role of Apoptosis in Age-Related Pathologies A review of recent data concerning the apoptotic death of cells during senescence at the organismic level. The data analyzed suggest interrelations between apoptosis deregulation and some age-related pathologies and senescent phenotypes. Genetic aspects and possible mechanisms of age-related changes in the program of apoptosis are considered. It has been proposed that age-related deregulation of apoptosis is a mechanism of senescence. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Russian Journal of Developmental Biology Springer Journals

Role of Apoptosis in Age-Related Pathologies

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Publisher
Springer Journals
Copyright
Copyright © 2001 by MAIK “Nauka/Interperiodica”
Subject
Life Sciences; Animal Anatomy / Morphology / Histology
ISSN
1062-3604
eISSN
1608-3326
D.O.I.
10.1023/A:1016766516285
Publisher site
See Article on Publisher Site

Abstract

A review of recent data concerning the apoptotic death of cells during senescence at the organismic level. The data analyzed suggest interrelations between apoptosis deregulation and some age-related pathologies and senescent phenotypes. Genetic aspects and possible mechanisms of age-related changes in the program of apoptosis are considered. It has been proposed that age-related deregulation of apoptosis is a mechanism of senescence.

Journal

Russian Journal of Developmental BiologySpringer Journals

Published: Oct 9, 2004

References

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