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Risperidone

Risperidone Reactions 1680, p299 - 2 Dec 2017 Idiopathic granulomatous mastitis with hyperprolactinaemia: case report A 55-year-old woman developed idiopathic granulomatous mastitis (IGM) with hyperprolactinaemia following the therapy with risperidone. The woman presented with a one month history of swelling and pain in her left breast. Subsequent core biopsies of the lesions demonstrated focal inflammation. Her medical history included depression and schizoaffective disorder, for which she was successfully treated with risperidone for a number of years [route and dosage not stated]. Examination showed a large mass with erythema and suppuration over the lateral aspect of her left breast. She had long standing bilateral nipple inversion. Based on the physical exam and biopsy, a presumptive diagnosis of infective duct ectasia was made. The woman received treatment with amoxicillin and clavulanic acid. However, after two weeks of the treatment, there was no improvement. The overlying skin had broken down and was suppurating. A further biopsy was conducted that confirmed the manifestation of the suspected IGM. Owing to the probability of the development of hyperprolactinaemia due to risperidone use, a serum prolactin level investigation was performed, which showed increased levels. Hence, she was diagnosed with risperidone induced hyperprolactinaemia, with associated IGM [duration of http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Risperidone

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017

Risperidone

Abstract

Reactions 1680, p299 - 2 Dec 2017 Idiopathic granulomatous mastitis with hyperprolactinaemia: case report A 55-year-old woman developed idiopathic granulomatous mastitis (IGM) with hyperprolactinaemia following the therapy with risperidone. The woman presented with a one month history of swelling and pain in her left breast. Subsequent core biopsies of the lesions demonstrated focal inflammation. Her medical history included depression and schizoaffective disorder, for which she was...
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References (1)

Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
DOI
10.1007/s40278-017-39230-4
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p299 - 2 Dec 2017 Idiopathic granulomatous mastitis with hyperprolactinaemia: case report A 55-year-old woman developed idiopathic granulomatous mastitis (IGM) with hyperprolactinaemia following the therapy with risperidone. The woman presented with a one month history of swelling and pain in her left breast. Subsequent core biopsies of the lesions demonstrated focal inflammation. Her medical history included depression and schizoaffective disorder, for which she was successfully treated with risperidone for a number of years [route and dosage not stated]. Examination showed a large mass with erythema and suppuration over the lateral aspect of her left breast. She had long standing bilateral nipple inversion. Based on the physical exam and biopsy, a presumptive diagnosis of infective duct ectasia was made. The woman received treatment with amoxicillin and clavulanic acid. However, after two weeks of the treatment, there was no improvement. The overlying skin had broken down and was suppurating. A further biopsy was conducted that confirmed the manifestation of the suspected IGM. Owing to the probability of the development of hyperprolactinaemia due to risperidone use, a serum prolactin level investigation was performed, which showed increased levels. Hence, she was diagnosed with risperidone induced hyperprolactinaemia, with associated IGM [duration of

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

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