Ribavirin/sofosbuvir Reactions 1680, p296 - 2 Dec 2017 Acute kidney injury: case report In a retrospective cohort study of 172 patients, a patient [age and sex not stated] developed acute kidney injury during treatment with ribavirin and sofosbuvir. The patient, who had a history of HIV and hepatitis C virus co-infection, started receiving treatment with ribavirin and sofosbuvir [routes and dosages not stated]. Twenty days later, the patient developed acute kidney injury secondary to significant nausea and vomiting. Subsequently, the patient was hospitalised for two days. The patient recovered after discontinuation of ribavirin and sofosbuvir therapy and undergoing supportive care. Author comment: "However, 1 of the 7 patients in the [ribavirin and sofosbuvir] group discontinued treatment prematurely because of [acute kidney injury]." Patel M, et al. Highly Successful Hepatitis C Virus (HCV) treatment outcomes in human immunodeficiency virus/HCV-coinfected patients at a large, urban, Ryan White clinic. Open Forum Infectious Diseases 4: ofx062, No. 2, 01 Apr 2017. Available from: URL: http://doi.org/10.1093/ofid/ofx062 - USA 803284076 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals


Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Springer International Publishing
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
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