Reactions 1680, p296 - 2 Dec 2017
Acute kidney injury: case report
In a retrospective cohort study of 172 patients, a patient [age
and sex not stated] developed acute kidney injury during
treatment with ribavirin and sofosbuvir. The patient, who had a
history of HIV and hepatitis C virus co-infection, started
receiving treatment with ribavirin and sofosbuvir [routes and
dosages not stated]. Twenty days later, the patient developed
acute kidney injury secondary to significant nausea and
vomiting. Subsequently, the patient was hospitalised for two
days. The patient recovered after discontinuation of ribavirin
and sofosbuvir therapy and undergoing supportive care.
Author comment: "However, 1 of the 7 patients in the
[ribavirin and sofosbuvir] group discontinued treatment
prematurely because of [acute kidney injury]."
Patel M, et al. Highly Successful Hepatitis C Virus (HCV) treatment outcomes in
human immunodeficiency virus/HCV-coinfected patients at a large, urban, Ryan
White clinic. Open Forum Infectious Diseases 4: ofx062, No. 2, 01 Apr 2017.
Available from: URL: http://doi.org/10.1093/ofid/ofx062 - USA
Reactions 2 Dec 2017 No. 16800114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved