Diabetologia (2017) 60:1770–1781 DOI 10.1007/s00125-017-4333-0 ARTICLE Retinal vascular geometry and 6 year incidence and progression of diabetic retinopathy 1,2 1,3 2 Carol Yim-lui Cheung & Charumathi Sabanayagam & Antony Kwan-pui Law & 1 1 1 4 Neelam Kumari & Daniel Shu-wei Ting & Gavin Tan & Paul Mitchell & 1,3,5 1,3,5 Ching Yu Cheng & Tien Yin Wong Received: 22 March 2017 /Accepted: 17 May 2017 /Published online: 16 June 2017 Springer-Verlag GmbH Germany 2017 Abstract liferative diabetic retinopathy or diabetic macular oedema at Aims/hypothesis We aimed to examine prospectively the as- follow-up in participants who had had no or mild non- sociation between a range of retinal vascular geometric vari- proliferative diabetic retinopathy at baseline. Progression of ables measured from retinal photographs and the 6 year inci- diabetic retinopathy was defined as an increase in severity of dence and progression of diabetic retinopathy. ≥2 steps at follow-up. Log-binomial models with an Methods We conducted a prospective, population-based co- expectation-maximisation algorithm were used to estimate hort study of Asian Malay individuals aged 40–80 years at RR adjusting for age, sex, diabetes duration, HbA level, 1c baseline (n = 3280) who returned for a 6 year follow-up. BP, BMI, estimated
Diabetologia – Springer Journals
Published: Jun 16, 2017
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