Graefes Arch Clin Exp Ophthalmol (2017) 255:1661–1668 DOI 10.1007/s00417-017-3713-y NEUROPHTHALMOLOGY Retinal microstructures are altered in patients with idiopathic infantile nystagmus 1,2 2 2,3 2 Jinu Han & Taekjune Lee & Jong Bok Lee & Sueng-Han Han Received: 11 October 2016 /Revised: 26 March 2017 /Accepted: 30 May 2017 /Published online: 14 June 2017 Springer-Verlag Berlin Heidelberg 2017 Abstract the two groups. At the nasal and temporal position where the Purpose To compare segmented retinal layer thicknesses be- ganglion cell density was thickest, the GCIPL thickness was tween patients with idiopathic infantile nystagmus (IIN) and thinner in the IIN group compared to the controls (99.5 μmvs. controls. 102.8 μm, P = 0.010). The GCIPL thickness was negatively Methods This retrospective case-control study included 66 correlated with logMAR visual acuity (Spearman’s patients with IIN and 66 age-matched controls. The retinal rho = −0.502, P <0.001). layers were examined using spectral domain optical coherence Conclusions The foveal pit was shallower, OSL was shorter, tomography with autosegmentation. Central foveal thickness and the GCIPL thicknesses at macular humps were decreased (CFT), outer nuclear layer (ONL), and outer segment length in the patients with IIN compared with that of controls. The (OSL) thickness were measured
Graefe's Archive for Clinical and Experimental Ophthalmology – Springer Journals
Published: Jun 14, 2017
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