Archives of Dermatological Research https://doi.org/10.1007/s00403-018-1839-3 LE T TER TO THE EDITOR Reply to the letter: “Can such an animal model truly represent Henoch–Schönlein purpura?” 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 1,2,3 Yanhong Li · Xiaolong Sui · Hua Zhu · Yanfeng Xu · Lan Huang · Yuhuan Xu · Yunlin Han · 4 1,2,3 Xiaochun Feng · Chuan Qin Received: 15 April 2018 / Accepted: 26 April 2018 © Springer-Verlag GmbH Germany, part of Springer Nature 2018 First of all, we would like to explain that animal models the results proved to be consistent with the literatures. are made to simulate a part or most of the characteristics This is mentioned in the discussion of the paper. of human disease, which does not fully represent human 2. The production of skin lesions of animals were accord- disease, and make it easier for workers to refer and utilize in ing to the Arthus hypersensitivity reactions type III, a certain aspect. We are very pleased with the attention and showed local swelling, hemorrhage or necrosis . As advice of the HSP animal model. We will actively improve for this, we also have discussed in the manuscript. The it, and hope all of us will work together to make animal vasculitis diseases of these
Archives of Dermatological Research – Springer Journals
Published: Jun 1, 2018
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