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Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial

Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post... Diabetes Ther (2018) 9:987–999 https://doi.org/10.1007/s13300-018-0403-7 ORIGINAL RESEARCH Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial . . . . Qing Su Jun Liu Pengfei Li Lei Qian Wenying Yang Received: October 26, 2017 / Published online: March 24, 2018 The Author(s) 2018 Methods: CLASSIFY is a phase IV, randomized, ABSTRACT open-label, 26-week, parallel-arm, treat-to-tar- get, multinational, controlled study in patients Introduction: Few prospective clinical trials with type 2 diabetes mellitus to compare the have investigated the role of fasting blood glu- efficacy and safety of insulin lispro mix 25 cose (FBG) and/or postprandial glucose (PPG) in (LM25) and insulin lispro mix 50 (LM50) as assessing overall glycemic control by using dif- starter insulins. Insulin was titrated with an aim ferent insulin regimens. In the present post hoc to target pre-meal blood glucose (BG) levels at analysis, we assessed the contribution of FBG [ 3.9 and B 6.1 mmol/L before breakfast and and/or PPG in overall glycemic control in Chi- dinner. The primary outcome assessed was the nese patients under insulin treatment. change in HbA1c from baseline. Results: Chinese patients contributed 38.7% Enhanced content To view enhanced http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Diabetes Therapy Springer Journals

Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial

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Publisher
Springer Journals
Copyright
Copyright © 2018 by The Author(s)
Subject
Medicine & Public Health; Internal Medicine; Diabetes; Cardiology; Endocrinology
ISSN
1869-6953
eISSN
1869-6961
DOI
10.1007/s13300-018-0403-7
Publisher site
See Article on Publisher Site

Abstract

Diabetes Ther (2018) 9:987–999 https://doi.org/10.1007/s13300-018-0403-7 ORIGINAL RESEARCH Relative Contribution of Fasting and Postprandial Blood Glucose in Overall Glycemic Control: Post Hoc Analysis of a Phase IV Randomized Trial . . . . Qing Su Jun Liu Pengfei Li Lei Qian Wenying Yang Received: October 26, 2017 / Published online: March 24, 2018 The Author(s) 2018 Methods: CLASSIFY is a phase IV, randomized, ABSTRACT open-label, 26-week, parallel-arm, treat-to-tar- get, multinational, controlled study in patients Introduction: Few prospective clinical trials with type 2 diabetes mellitus to compare the have investigated the role of fasting blood glu- efficacy and safety of insulin lispro mix 25 cose (FBG) and/or postprandial glucose (PPG) in (LM25) and insulin lispro mix 50 (LM50) as assessing overall glycemic control by using dif- starter insulins. Insulin was titrated with an aim ferent insulin regimens. In the present post hoc to target pre-meal blood glucose (BG) levels at analysis, we assessed the contribution of FBG [ 3.9 and B 6.1 mmol/L before breakfast and and/or PPG in overall glycemic control in Chi- dinner. The primary outcome assessed was the nese patients under insulin treatment. change in HbA1c from baseline. Results: Chinese patients contributed 38.7% Enhanced content To view enhanced

Journal

Diabetes TherapySpringer Journals

Published: Mar 24, 2018

References