Curr Trop Med Rep (2017) 4:127–135 DOI 10.1007/s40475-017-0119-1 MELIOIDOSIS AND TROPICAL BACTERIOLOGY (A TORRES, SECTION EDITOR) Relationships Between Resistance and Virulence in Burkholderia pseudomallei 1 1 1 1,2 Marine Schnetterle & Lionel Koch & Olivier Gorgé & Eric Valade & 3 1 1 Jean-Michel Bolla & Fabrice Biot & Fabienne Neulat-Ripoll Published online: 2 August 2017 Springer International Publishing AG 2017 . . Abstract Keywords Burkholderia pseudomallei Melioidosis Purpose of Review Aroused by the capacity of bacteria to Antibiotic resistance Virulence develop antimicrobial resistance which allows them to persist in patient under antibiotic treatment, and their adaptation to host defenses by modifying their virulence, we review the relationship between antibiotic resistance and virulence in Introduction Burkholderia pseudomallei. Recent Finding Few studies focused on both antibiotic resis- Burkholderia pseudomallei is the causal agent of tance and virulence. The relationship between these two melioidosis, an endemic human disease mostly present in mechanisms is very complex. Main resistance mechanisms Southern Asia and Northern Australia. The endemic such as efflux, biofilm, morphological changes or persistence area has been recently expanded to other countries are linked to virulence but results are still controversial. and risk zones are also observed in Central America, Recent clinical
Current Tropical Medicine Reports – Springer Journals
Published: Aug 2, 2017
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