email@example.com Instituto de Investigación Biomédica de Salamanca (IBSAL), Salamanca, Spain Servicio de Traumatología y Cirugía Ortopédica, Hospital Universitario de Salamanca, Salamanca, Spain BIOFORGE Lab, Universidad de Valladolid, CIBER-BBN, Paseo de Belén, 19, 47011 Valladolid, Spain Technical Proteins Nanobiotechnology (TPNBT), Valladolid, Spain Unidad de Terapia Celular. Servicio de Hematología, Hospital Universitario de Salamanca, Salamanca, Spain 1 Introduction Departamento de Biología Celular y Patología, Universidad de Salamanca, Salamanca, Spain Osteochondral injuries are a frequent source of pain and Servicio de Radiodiagnóstico, Hospital Virgen de la Concha de Zamora, Zamora, Spain disability and can even result in secondary osteoarthritis . 115 Page 2 of 11 J Mater Sci: Mater Med (2017) 28:115 This disease has an enormous economic impact in devel- well-known RGD cell-adhesion sequence, which promotes oped countries, mostly due to ageing . One of the main speciﬁc cell attachment via integrins , leads to an issues in this regard is that articular cartilage possesses injectable scaffold that provides a cell-friendly limited regeneration ability due to its avascularity and the environment. cellular and interstitial structure that sustains the bio- With regard to the tracking of cartilage regeneration, mechanical requirements of joints . As such, it is easy to non-invasive imaging techniques
Journal of Materials Science: Materials in Medicine – Springer Journals
Published: Jun 24, 2017
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