Journal of Gastrointestinal Cancer https://doi.org/10.1007/s12029-018-0124-1 CASE REPORT Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus—a Case Report and Review of Literature 1 1 1 2 3 4 2 Hamza Arif & Moeezullah Beg & Sohaib Zahid & Moaz Sial & Aditya Talwar & Antonios Christou & Michael Babich Springer Science+Business Media, LLC, part of Springer Nature 2018 Introduction However, we present a patient with metastatic SCC of the esophagus with hypercalcemia but with elevated serum levels Hypercalcemia is a commonly encountered issue in malignan- of both PTH and PTHrP. This appears to be the first case of cy, occurring in nearly 20 to 30% of patients at some point SCC of the esophagus with an increase in both PTH and during their disease course . Although malignancy, includ- PTHrP. ing squamous cell carcinomas (SCC), and primary hyperpara- thyroidism are most frequently associated with hypercalcemia other causeshavealsobeenidentified. Hypercalcemia of Case Report malignancy in solid tumors is a poor prognostic sign and near- ly 50% of patients die within 30 days . Lung and breast A 62-year-old male patient presented with a serum calcium of cancer are two of the most common causes of hypercalcemia 16.7 mg/dL (reference range [ref]
Journal of Gastrointestinal Cancer – Springer Journals
Published: Jun 4, 2018
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