Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus—a Case Report and Review of Literature

Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus—a Case Report and Review... Journal of Gastrointestinal Cancer https://doi.org/10.1007/s12029-018-0124-1 CASE REPORT Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus—a Case Report and Review of Literature 1 1 1 2 3 4 2 Hamza Arif & Moeezullah Beg & Sohaib Zahid & Moaz Sial & Aditya Talwar & Antonios Christou & Michael Babich Springer Science+Business Media, LLC, part of Springer Nature 2018 Introduction However, we present a patient with metastatic SCC of the esophagus with hypercalcemia but with elevated serum levels Hypercalcemia is a commonly encountered issue in malignan- of both PTH and PTHrP. This appears to be the first case of cy, occurring in nearly 20 to 30% of patients at some point SCC of the esophagus with an increase in both PTH and during their disease course [1]. Although malignancy, includ- PTHrP. ing squamous cell carcinomas (SCC), and primary hyperpara- thyroidism are most frequently associated with hypercalcemia other causeshavealsobeenidentified[2]. Hypercalcemia of Case Report malignancy in solid tumors is a poor prognostic sign and near- ly 50% of patients die within 30 days [3]. Lung and breast A 62-year-old male patient presented with a serum calcium of cancer are two of the most common causes of hypercalcemia 16.7 mg/dL (reference range [ref] http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Gastrointestinal Cancer Springer Journals

Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus—a Case Report and Review of Literature

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Publisher
Springer US
Copyright
Copyright © 2018 by Springer Science+Business Media, LLC, part of Springer Nature
Subject
Medicine & Public Health; Oncology; Gastroenterology; Radiotherapy; Cancer Research; Internal Medicine
ISSN
1941-6628
eISSN
1941-6636
D.O.I.
10.1007/s12029-018-0124-1
Publisher site
See Article on Publisher Site

Abstract

Journal of Gastrointestinal Cancer https://doi.org/10.1007/s12029-018-0124-1 CASE REPORT Refractory Hypercalcemia in Squamous Cell Carcinoma of the Esophagus—a Case Report and Review of Literature 1 1 1 2 3 4 2 Hamza Arif & Moeezullah Beg & Sohaib Zahid & Moaz Sial & Aditya Talwar & Antonios Christou & Michael Babich Springer Science+Business Media, LLC, part of Springer Nature 2018 Introduction However, we present a patient with metastatic SCC of the esophagus with hypercalcemia but with elevated serum levels Hypercalcemia is a commonly encountered issue in malignan- of both PTH and PTHrP. This appears to be the first case of cy, occurring in nearly 20 to 30% of patients at some point SCC of the esophagus with an increase in both PTH and during their disease course [1]. Although malignancy, includ- PTHrP. ing squamous cell carcinomas (SCC), and primary hyperpara- thyroidism are most frequently associated with hypercalcemia other causeshavealsobeenidentified[2]. Hypercalcemia of Case Report malignancy in solid tumors is a poor prognostic sign and near- ly 50% of patients die within 30 days [3]. Lung and breast A 62-year-old male patient presented with a serum calcium of cancer are two of the most common causes of hypercalcemia 16.7 mg/dL (reference range [ref]

Journal

Journal of Gastrointestinal CancerSpringer Journals

Published: Jun 4, 2018

References

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