ORIGINAL ARTICLE Reducing the small-heart effect in pediatric gated myocardial perfusion single-photon emission computed tomography a b c Hiroto Yoneyama, PhD, Kenichi Nakajima, MD, Koichi Okuda, PhD, b d b Shinro Matsuo, MD, Masahisa Onoguchi, PhD, Seigo Kinuya, MD, and Lars Edenbrandt, MD, PhD Department of Radiological Technology, Kanazawa University Hospital, Kanazawa, Japan Department of Nuclear Medicine, Kanazawa University Hospital, Kanazawa, Japan Department of Physics, Kanazawa Medical University, Kanazawa, Japan Department of Health Science, Graduate School of Medical Science, Kanazawa University, Kanazawa, Japan Department of Molecular and Clinical Medicine, University of Gothenburg, Gothenburg, Sweden Received Nov 7, 2015; accepted Apr 10, 2016 doi:10.1007/s12350-016-0518-z Background. We compared two reconstruction algorisms and two cardiac functional evaluation software programs in terms of their accuracy for estimating ejection fraction (EF) of small hearts (SH). Methods. The study group consisted of 66 pediatric patients. Data were reconstructed using a ﬁltered back projection (FBP) method without the resolution correction (RC) and an iterative method based on an ordered subset expectation maximization (OSEM) algorithm with the RC. EF was evaluated using two software programs of quantitative gated single-photon emission computed tomography (SPECT) (QGS) and cardioREPO. We compared the EF of gated myocardial perfusion SPECT to echocardiographic
Journal of Nuclear Cardiology – Springer Journals
Published: May 19, 2016
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