difference regarding image sharpness (P = 0.59). There Purpose: To compare image quality and lesion conspicu- were subjectively more artifacts on RD CT (P < 0.01). ity of reduced dose (RD) CT with model-based iterative Lesion conspicuity was subjectively better in RD CT reconstruction (MBIR) compared to standard dose (SD) (P < 0.01). Repeated target lesion size measurements CT in patients undergoing oncological follow-up imag- were highly reproducible both on SD CT (ICC = 0.987) ing. and RD CT (ICC = 0.97). Methods: Forty-four cancer patients who had a staging Conclusions: RD CT imaging with MBIR provides SD CT within 12 months were prospectively included to diagnostic imaging quality and comparable lesion con- undergo a weight-based RD CT with MBIR. Radiation spicuity on follow-up exams while allowing dose reduc- dose was recorded and tissue attenuation and image tion by a median of 46% compared to SD CT imaging. noise of four tissue types were measured. Reproducibility of target lesion size measurements of up to 5 target Key words: Radiation dose reduction—Image lesions per patient were analyzed. Subjective image noise—Computer tomography—Cancer—Model-based quality was evaluated for three readers independently iterative reconstruction (MBIR) utilizing 4- or 5-point Likert scales. Results: Median radiation
Abdominal Radiology – Springer Journals
Published: Apr 17, 2017
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