Access the full text.
Sign up today, get DeepDyve free for 14 days.
G. Scheef, N. Fischer, Ulrich Krach, R. Tönjes (2001)
The Number of a U3 Repeat Box Acting as an Enhancer in Long Terminal Repeats of Polytropic Replication-Competent Porcine Endogenous Retroviruses Dynamically Fluctuates during Serial Virus Passages in Human CellsJournal of Virology, 75
P. Tissier, J. Stoye, Y. Takeuchi, C. Patience, R. Weiss (1997)
Two sets of human-tropic pig retrovirusNature, 389
Y Takeuchi, C Patience, S Magre, RA Weiss, PT Banerjee, P Le Tissier, JP Stoye (1998)
Infection of human cells by an endogenous retrovirus of pigsJ Virol, 72
Stanley Martin, R. Wilkinson, J. Fishman (2006)
Genomic presence of recombinant porcine endogenous retrovirus in transmitting miniature swineVirology Journal, 3
A. Tucker, C. Belcher, Badru Moloo, J. Bell, T. Mazzulli, A. Humar, A. Hughes, P. McArdle, A. Talbot (2002)
The production of transgenic pigs for potential use in clinical xenotransplantation: microbiological evaluationXenotransplantation, 9
R. Villanueva, S. Campbell, M. Roth (2003)
Molecular analysis of a recombinant M-MuLV/RaLV retrovirus.Virology, 315 1
S. Tacke, Reinhard Kurth, J. Denner (2000)
Porcine endogenous retroviruses inhibit human immune cell function: risk for xenotransplantation?Virology, 268 1
J. Denner (1998)
Immunosuppression by Retroviruses: Implications for XenotransplantationAnnals of the New York Academy of Sciences, 862
V. Specke, S. Rubant, J. Denner (2001)
Productive infection of human primary cells and cell lines with porcine endogenous retroviruses.Virology, 285 2
U. Martin, V. Kiessig, J. Blusch, A. Haverich, Prof. Steinhoff (1998)
Expression of pig endogenous retrovirus by primary porcine endothelial cells and infection of human cellsThe Lancet, 352
J Denner (1998)
Immunosuppression by retroviruses: implications for xenotransplantationAnn NY Acad Sci, 862
S. Tacke, V. Specke, J. Denner (2003)
Differences in Release and Determination of Subtype of Porcine Endogenous Retroviruses Produced by Stimulated Normal Pig Blood CellsIntervirology, 46
E. Murphy, B. Korber, M. Georges-Courbot, B. You, A. Pinter, Debra Cook, M. Kieny, A. Georges, C. Mathiot, F. Barré-Sinoussi, M. Girard (1993)
Diversity of V3 region sequences of human immunodeficiency viruses type 1 from the central African Republic.AIDS research and human retroviruses, 9 10
James Wood, G. Quinn, K. Suling, B. Oldmixon, B. Tine, R. Cina, S. Arn, Christine Huang, L. Scobie, D. Onions, D. Sachs, H. Schuurman, J. Fishman, C. Patience (2004)
Identification of Exogenous Forms of Human-Tropic Porcine Endogenous Retrovirus in Miniature SwineJournal of Virology, 78
U. Martin, M. Winkler, M. Id, H. Radeke, L. Arseniev, Y. Takeuchi, A. Simon, C. Patience, A. Haverich, Prof. Steinhoff (2000)
Productive infection of primary human endothelial cells by pig endogenous retrovirus (PERV)Xenotransplantation, 7
F. Konings, S. Burda, Mateusz Urbanski, P. Zhong, A. Nadas, P. Nyambi (2006)
Human immunodeficiency virus type 1 (HIV‐1) circulating recombinant form 02_AG (CRF02_AG) has a higher in vitro replicative capacity than its parental subtypes A and GJournal of Medical Virology, 78
J. Blusch, C. Patience, Y. Takeuchi, C. Templin, C. Roos, K. Helm, Prof. Steinhoff, U. Martin (2000)
Infection of Nonhuman Primate Cells by Pig Endogenous RetrovirusJournal of Virology, 74
C. Patience, Y. Takeuchi, R. Weiss (1997)
Infection of human cells by an endogenous retrovirus of pigsNature Medicine, 3
S. Delassus, P. Sonigo, S. Wain-Hobson (1989)
Genetic organization of gibbon ape leukemia virus.Virology, 173 1
Peter Donahue, E. Hoover, G. Beltz, N. Riedel, Vanessa Hirsch, Julie Overbaugh, James Mullins (1988)
Strong sequence conservation among horizontally transmissible, minimally pathogenic feline leukemia virusesJournal of Virology, 62
Maria Anderson, A. Lauring, S. Robertson, C. Dirks, J. Overbaugh (2001)
Feline Pit2 Functions as a Receptor for Subgroup B Feline Leukemia VirusesJournal of Virology, 75
V. Specke, V. Specke, S. Tacke, K. Boller, Jochen Schwendemann, J. Denner, J. Denner (2001)
Porcine endogenous retroviruses: in vitro host range and attempts to establish small animal models.The Journal of general virology, 82 Pt 4
Hung Fan (1997)
Leukemogenesis by Moloney murine leukemia virus: a multistep process.Trends in microbiology, 5 2
B. Oldmixon, James Wood, T. Ericsson, Carolyn Wilson, M. White-Scharf, G. Andersson, J. Greenstein, H. Schuurman, C. Patience (2002)
Porcine Endogenous Retrovirus Transmission Characteristics of an Inbred Herd of Miniature SwineJournal of Virology, 76
V. Specke, R. Plesker, Cheick Coulibaly, Klaus Boller, J. Denner (2002)
Productive infection of a mink cell line with porcine endogenous retroviruses (PERVs) but lack of transmission to minks in vivoArchives of Virology, 147
Malou Gemeniano, O. Mpanju, D. Salomon, M. Eiden, Carolyn Wilson (2006)
The infectivity and host range of the ecotropic porcine endogenous retrovirus, PERV-C, is modulated by residues in the C-terminal region of its surface envelope protein.Virology, 346 1
V. Specke, Henk-Jan Schuurman, R. Plesker, Cheick Coulibaly, M. Özel, G. Langford, Reinhard Kurth, J. Denner (2002)
Virus safety in xenotransplantation: first exploratory in vivo studies in small laboratory animals and non-human primates.Transplant immunology, 9 2-4
Carolyn Wilson, Susan Wong, M. VanBrocklin, M. Federspiel (2000)
Extended Analysis of the In Vitro Tropism of Porcine Endogenous RetrovirusJournal of Virology, 74
R. Mendoza, Maria Anderson, J. Overbaugh (2006)
A Putative Thiamine Transport Protein Is a Receptor for Feline Leukemia Virus Subgroup AJournal of Virology, 80
Britta Dieckhoff, J. Puhlmann, Kristina Büscher, A. Hafner-Marx, N. Herbach, N. Bannert, M. Büttner, R. Wanke, R. Kurth, J. Denner (2007)
Expression of porcine endogenous retroviruses (PERVs) in melanomas of Munich miniature swine (MMS) Troll.Veterinary microbiology, 123 1-3
N. Vidal, M. Peeters, C. Mulanga-Kabeya, N. Nzilambi, D. Robertson, Wantabala Ilunga, H. Sema, K. Tshimanga, Beni Bongo, E. Delaporte (2000)
Unprecedented Degree of Human Immunodeficiency Virus Type 1 (HIV-1) Group M Genetic Diversity in the Democratic Republic of Congo Suggests that the HIV-1 Pandemic Originated in Central AfricaJournal of Virology, 74
V. Courgnaud, M. Salemi, X. Pourrut, E. Mpoudi-Ngolé, Bernadette Abela, P. Auzel, F. Bibollet-Ruche, B. Hahn, A. Vandamme, E. Delaporte, M. Peeters (2002)
Characterization of a Novel Simian Immunodeficiency Virus with a vpu Gene from Greater Spot-Nosed Monkeys (Cercopithecus nictitans) Provides New Insights into Simian/Human Immunodeficiency Virus PhylogenyJournal of Virology, 76
Carolyn Wilson, Susan Wong, J. Muller, C. Davidson, T. Rose, P. Burd (1998)
Type C Retrovirus Released from Porcine Primary Peripheral Blood Mononuclear Cells Infects Human CellsJournal of Virology, 72
Matiza McIntyre, Bhanumathi Kannan, G. Solano-Aguilar, Carolyn Wilson, E. Bloom (2003)
Detection of porcine endogenous retrovirus in cultures of freshly isolated porcine bone marrow cellsXenotransplantation, 10
Chunfu Yang, Bipin Dash, Sheri Hanna, Henry Frances, N. Nzilambi, R. Colebunders, Michael Louis, Thomas Quinn, T. Folks, R. Lal (2001)
Predominance of HIV type 1 subtype G among commercial sex workers from Kinshasa, Democratic Republic of Congo.AIDS research and human retroviruses, 17 4
Yasuhiro Takeuchi, Richard Vile, Guy Simpson, B. O'hara, Mary Collins, Robin Weiss (1992)
Feline leukemia virus subgroup B uses the same cell surface receptor as gibbon ape leukemia virusJournal of Virology, 66
B. Bartosch, D. Stefanidis, R. Myers, R. Weiss, C. Patience, Y. Takeuchi (2004)
Evidence and Consequence of Porcine Endogenous Retrovirus RecombinationJournal of Virology, 78
S. Perryman, Jane Nishio, Bruce Chesebro (1991)
Complete nucleotide sequence of Friend murine leukemia virus, strain FB29.Nucleic acids research, 19 24
A. Barnett, David Wensel, Weihua Li, D. Fass, J. Cunningham (2003)
Structure and Mechanism of a Coreceptor for Infection by a Pathogenic Feline RetrovirusJournal of Virology, 77
JIN-YOUNG Han, Paula Cannon, KIN-MAN Lai, Yi Zhao, M. Eiden, W. Anderson (1997)
Identification of envelope protein residues required for the expanded host range of 10A1 murine leukemia virusJournal of Virology, 71
Y. Takeuchi, C. Patience, S. Magre, R. Weiss, P. Banerjee, P. Tissier, J. Stoye (1998)
Host Range and Interference Studies of Three Classes of Pig Endogenous RetrovirusJournal of Virology, 72
K. Motomura, Jianbo Chen, Wei-Shau Hu (2007)
Genetic Recombination between Human Immunodeficiency Virus Type 1 (HIV-1) and HIV-2, Two Distinct Human LentivirusesJournal of Virology, 82
F. Simon, P. Mauclère, P. Roques, I. Loussert‐Ajaka, M. Müller-Trutwin, S. Saragosti, M. Georges-Courbot, F. Barré-Sinoussi, F. Brun-vezinet (1998)
Identification of a new human immunodeficiency virus type 1 distinct from group M and group ONature Medicine, 4
J. Denner, V. Specke, Ulla Thiesen, A. Karlas, R. Kurth (2003)
Genetic alterations of the long terminal repeat of an ecotropic porcine endogenous retrovirus during passage in human cells.Virology, 314 1
Ian Harrison, Y. Takeuchi, B. Bartosch, J. Stoye (2004)
Determinants of High Titer in Recombinant Porcine Endogenous RetrovirusesJournal of Virology, 78
Dimitrios Paraskevis, P. Lemey, Marco Salemi, M. Suchard, Y. Peer, A. Vandamme (2003)
Analysis of the evolutionary relationships of HIV-1 and SIVcpz sequences using bayesian inference: implications for the origin of HIV-1.Molecular biology and evolution, 20 12
I. Suzuka, N. Shimizu, K. Sekiguchi, H. Hoshino, M. Kodama, K. Shimotohno (1986)
Molecular cloning of unintegrated closed circular DNA of porcine retrovirusFEBS Letters, 198
F. Gao, E. Bailes, D. Robertson, Yalu Chen, C. Rodenburg, S. Michael, L. Cummins, L. Arthur, M. Peeters, G. Shaw, P. Sharp, B. Hahn (1999)
Origin of HIV-1 in the chimpanzee Pan troglodytes troglodytesNature, 397
R. Leys, B. Vanderborght, M. Haesevelde, L. Heyndrickx, A. Geel, C. Wauters, R. Bernaerts, E. Saman, P. Nijs, B. Willems (1990)
Isolation and partial characterization of an unusual human immunodeficiency retrovirus from two persons of west-central African originJournal of Virology, 64
T. Ericsson, Y. Takeuchi, C. Templin, G. Quinn, S. Farhadian, James Wood, B. Oldmixon, K. Suling, J. Ishii, Y. Kitagawa, T. Miyazawa, D. Salomon, R. Weiss, C. Patience (2003)
Identification of receptors for pig endogenous retrovirusProceedings of the National Academy of Sciences of the United States of America, 100
V Specke, HJ Schuurman, R Plesker, C Coulibaly, M Özel, G Langford, R Kurth, J Denner (2002)
Virus safety in xenotransplantation: preliminary data from first small animal and non-human primate in vivo experimentsTranspl Immunol, 9
T. Ericsson, B. Oldmixon, J. Blomberg, Margaret Rosa, C. Patience, G. Andersson (2001)
Identification of Novel Porcine Endogenous Betaretrovirus Sequences in Miniature SwineJournal of Virology, 75
P. Charneau, A. Borman, C. Quillent, D. Guétard, S. Chamaret, Jacques Cohen, G. Rémy, L. Montagnier, F. Clavel (1994)
Isolation and envelope sequence of a highly divergent HIV-1 isolate: definition of a new HIV-1 group.Virology, 205 1
C. Patience, W. Switzer, Y. Takeuchi, D. Griffiths, Melanie Goward, W. Heneine, J. Stoye, R. Weiss (2001)
Multiple Groups of Novel Retroviral Genomes in Pigs and Related SpeciesJournal of Virology, 75
P. Roy-burman (2005)
Endogenousenv elements: Partners in generation of pathogenic feline leukemia virusesVirus Genes, 11
Wei-Shau Hu, H. Temin (1990)
Genetic consequences of packaging two RNA genomes in one retroviral particle: pseudodiploidy and high rate of genetic recombination.Proceedings of the National Academy of Sciences of the United States of America, 87
U. Fiebig, M. Hartmann, N. Bannert, R. Kurth, J. Denner (2006)
Transspecies Transmission of the Endogenous Koala RetrovirusJournal of Virology, 80
J. Denner (2007)
Transspecies transmissions of retroviruses: new cases.Virology, 369 2
David Wensel, Weihua Li, J. Cunningham (2003)
A Virus-Virus Interaction Circumvents the Virus Receptor Requirement for Infection by Pathogenic RetrovirusesJournal of Virology, 77
DH Sachs, M Sykes, SC Robson, DK Cooper (2001)
XenotransplantationAdv Immunol, 79
V. Moennig, H. Frank, G. Hunsmann, Peter Ohms, H. Schwarz, W. Schäfer, H. Strandström (1974)
C-type particles produced by a permanent cell line from a leukemic pig. II. Physical, chemical, and serological characterization of the particles.Virology, 57 1
M. Frazier (2005)
Evidence for retrovirus in miniature swine with radiation-induced leukemia or metaplasiaArchives of Virology, 83
G. Mattiuzzo, M. Matoušková, Y. Takeuchi (2007)
Differential resistance to cell entry by porcine endogenous retrovirus subgroup A in rodent speciesRetrovirology, 4
R. Mang, J. Maas, Xianghong Chen, J. Goudsmit, A. Kuyl (2001)
Identification of a novel type C porcine endogenous retrovirus: evidence that copy number of endogenous retroviruses increases during host inbreeding.The Journal of general virology, 82 Pt 8
L. Gurtler, Peter Hauser, Josef Eberle, '. Albrecht, V. Brunn, S. Knapp, L. Zekeng, J. Tsague, L. Kaptue (1994)
A new subtype of human immunodeficiency virus type 1 (MVP-5180) from CameroonJournal of Virology, 68
Dimitri Lavillette, D. Kabat (2004)
Porcine Endogenous Retroviruses Infect Cells Lacking Cognate Receptors by an Alternative Pathway: Implications for Retrovirus Evolution and XenotransplantationJournal of Virology, 78
PERVs are integrated in the genome of all pigs. Some of them infect human cells and represent therefore a potential risk for xenotransplantation using pig cells or organs. Three replication-competent subtypes have been described, PERV-A, PERV-B and PERV-C. Whereas PERV-A and PERV-B are polytropic viruses and infect, among others, human cells, PERV-C is an ecotropic virus, infecting only pig cells. Recombinant PERV-A/C are able to infect human cells, they are characterised by high-titre replication and their proviruses have been found de novo integrated in the genome of somatic pig cells, but not in the germ line. This review compares recombinant PERVs with other recombinant retroviruses in order to evaluate their potential pathogenicity.
Archives of Virology – Springer Journals
Published: Aug 1, 2008
Read and print from thousands of top scholarly journals.
Already have an account? Log in
Bookmark this article. You can see your Bookmarks on your DeepDyve Library.
To save an article, log in first, or sign up for a DeepDyve account if you don’t already have one.
Copy and paste the desired citation format or use the link below to download a file formatted for EndNote
Access the full text.
Sign up today, get DeepDyve free for 14 days.
All DeepDyve websites use cookies to improve your online experience. They were placed on your computer when you launched this website. You can change your cookie settings through your browser.