Recent developments in the heterocyclic ketene aminal-based synthesis of heterocycles

Recent developments in the heterocyclic ketene aminal-based synthesis of heterocycles Small poly-functionalized heterocycles are frequently found in pharmacophores and play important roles in drug discovery. Heterocyclic ketene aminals (HKAs) are versatile building blocks for the synthesis of a variety of heterocyclic compounds. In recent years, there has been significant progress in the chemistry of HKAs. All previous work focused on the developments of HKAs in reaction type. This review focused on the developments of HKA-based synthesis of various heterocyclic nuclei since 2002. We believe this will give some insights and help to bring about new ideas for further research. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Research on Chemical Intermediates Springer Journals

Recent developments in the heterocyclic ketene aminal-based synthesis of heterocycles

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Publisher
Springer Netherlands
Copyright
Copyright © 2016 by Springer Science+Business Media Dordrecht
Subject
Chemistry; Catalysis; Physical Chemistry; Inorganic Chemistry
ISSN
0922-6168
eISSN
1568-5675
D.O.I.
10.1007/s11164-015-2391-9
Publisher site
See Article on Publisher Site

Abstract

Small poly-functionalized heterocycles are frequently found in pharmacophores and play important roles in drug discovery. Heterocyclic ketene aminals (HKAs) are versatile building blocks for the synthesis of a variety of heterocyclic compounds. In recent years, there has been significant progress in the chemistry of HKAs. All previous work focused on the developments of HKAs in reaction type. This review focused on the developments of HKA-based synthesis of various heterocyclic nuclei since 2002. We believe this will give some insights and help to bring about new ideas for further research.

Journal

Research on Chemical IntermediatesSpringer Journals

Published: Jan 11, 2016

References

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