Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases

Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases Drugs - Real World Outcomes (2017) 4:175–182 DOI 10.1007/s40801-017-0112-y ORIGINAL RESEARCH ARTICLE Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases 1 1 2 3 • • • • Liuqin Liang Donging Chen Xiaodong Wang Zheng Yang 1 1 1 • • Jun Zhou Zhongping Zhan Fan Lian Published online: 23 June 2017 The Author(s) 2017. This article is an open access publication Abstract hydration, and bladder irrigation. The other two were Objective The aim of this study was to investigate the unresponsive to the above treatment and finally had reso- prevalence, severity, risk factors, and treatment outcomes lution after cystectomy. The average resolution time of of cyclophosphamide (CYC)-induced hemorrhagic cystitis hematuria was 39.5 days (7–56 days). There were no (HC) in patients with rheumatic diseases. deaths in our cohort. Methods We collected the clinical data from 1284 con- Conclusion CYC-induced HC was rare and highly variable secutive patients admitted to The First Affiliated Hospital in Chinese patients with rheumatic diseases. Individualized of Sun Yat-Sen University who were treated with CYC treatment should be performed according to the severity of between 2006 and 2016, and then conducted a retrospective HC for each patient. More aggressive treatment strategies http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Drugs - Real World Outcomes Springer Journals

Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases

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Publisher
Springer International Publishing
Copyright
Copyright © 2017 by The Author(s)
Subject
Medicine & Public Health; Pharmacotherapy; Pharmacology/Toxicology; Internal Medicine
ISSN
2199-1154
eISSN
2198-9788
D.O.I.
10.1007/s40801-017-0112-y
Publisher site
See Article on Publisher Site

Abstract

Drugs - Real World Outcomes (2017) 4:175–182 DOI 10.1007/s40801-017-0112-y ORIGINAL RESEARCH ARTICLE Rare Cyclophosphamide-Induced Hemorrhagic Cystitis in a Chinese Population with Rheumatic Diseases 1 1 2 3 • • • • Liuqin Liang Donging Chen Xiaodong Wang Zheng Yang 1 1 1 • • Jun Zhou Zhongping Zhan Fan Lian Published online: 23 June 2017 The Author(s) 2017. This article is an open access publication Abstract hydration, and bladder irrigation. The other two were Objective The aim of this study was to investigate the unresponsive to the above treatment and finally had reso- prevalence, severity, risk factors, and treatment outcomes lution after cystectomy. The average resolution time of of cyclophosphamide (CYC)-induced hemorrhagic cystitis hematuria was 39.5 days (7–56 days). There were no (HC) in patients with rheumatic diseases. deaths in our cohort. Methods We collected the clinical data from 1284 con- Conclusion CYC-induced HC was rare and highly variable secutive patients admitted to The First Affiliated Hospital in Chinese patients with rheumatic diseases. Individualized of Sun Yat-Sen University who were treated with CYC treatment should be performed according to the severity of between 2006 and 2016, and then conducted a retrospective HC for each patient. More aggressive treatment strategies

Journal

Drugs - Real World OutcomesSpringer Journals

Published: Jun 23, 2017

References

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