A rapid screening and determination of 150 veterinary drugs of various classes in milk by UHPLC–high-resolution quadrupole time-of-flight mass spectrometry is proposed. One gram of milk was used for the analysis; the precipitation of proteins and extraction were performed with acetonitrile; the extract was analyzed without purification or preconcentration. Veterinary drugs were identified by accurate masses of analyte ions produced by electrospray ionization, their retention time, and the pattern of ion isotope distribution (mSigma). The quantitative analysis of the detected analytes was carried out by the standard addition method. The limits of detection were 0.1–0.5 ng/g; the analytical ranges were (0.1)1–500 ng/g; the duration of screening was 20–30 min; and the analysis time was 30–40 min. The relative standard deviation of the results for all analytes did not exceed 15%.
Journal of Analytical Chemistry – Springer Journals
Published: Jun 1, 2018
It’s your single place to instantly
discover and read the research
that matters to you.
Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.
All for just $49/month
Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly
Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.
Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.
Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.
All the latest content is available, no embargo periods.
“Hi guys, I cannot tell you how much I love this resource. Incredible. I really believe you've hit the nail on the head with this site in regards to solving the research-purchase issue.”Daniel C.
“Whoa! It’s like Spotify but for academic articles.”@Phil_Robichaud
“I must say, @deepdyve is a fabulous solution to the independent researcher's problem of #access to #information.”@deepthiw
“My last article couldn't be possible without the platform @deepdyve that makes journal papers cheaper.”@JoseServera