Randomized, double-blind, placebo-controlled trial to compare solifenacin versus trospium chloride in the relief of double-J stent-related symptoms

Randomized, double-blind, placebo-controlled trial to compare solifenacin versus trospium... World J Urol (2017) 35:1261–1268 DOI 10.1007/s00345-016-1988-y ORIGINAL ARTICLE Randomized, double‑blind, placebo‑controlled trial to compare solifenacin versus trospium chloride in the relief of double‑J stent‑related symptoms 1 2 1 Mohamed H. Abdelhamid · Ahmed S. Zayed · Waleed E. Ghoneima · 3 1 3 3 Akrm A. Elmarakbi · Mohamed S. El Sheemy · Ahmed Aref · Ahmed Abdelbary · Hani H. Nour Received: 19 September 2016 / Accepted: 4 December 2016 / Published online: 3 January 2017 © Springer-Verlag Berlin Heidelberg 2017 Abstract mean scores across all groups. Drug-related side effects, Purpose We aimed to compare the safety and efficacy of particularly constipation, were higher in trospium group solifenacin versus trospium chloride and compare each than in solifenacin one. drug versus placebo regarding the relief of stent-related Conclusions Solifenacin treatment showed significant symptoms following uncomplicated ureteroscopic litho- improvement in almost all domains of stent-related symp- tripsy (URSL). toms than trospium. In terms of safety and tolerance, both Methods In a prospective, randomized, double-blind study, drugs were comparable. Future studies should be designed 210 eligible patients who underwent URSL with double- to address the impact of combined drugs and lower doses in J stent insertion were recruited and randomly http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png World Journal of Urology Springer Journals

Randomized, double-blind, placebo-controlled trial to compare solifenacin versus trospium chloride in the relief of double-J stent-related symptoms

Loading next page...
 
/lp/springer_journal/randomized-double-blind-placebo-controlled-trial-to-compare-na1jmLorhM
Publisher
Springer Berlin Heidelberg
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Urology; Nephrology; Oncology
ISSN
0724-4983
eISSN
1433-8726
D.O.I.
10.1007/s00345-016-1988-y
Publisher site
See Article on Publisher Site

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 12 million articles from more than
10,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Unlimited reading

Read as many articles as you need. Full articles with original layout, charts and figures. Read online, from anywhere.

Stay up to date

Keep up with your field with Personalized Recommendations and Follow Journals to get automatic updates.

Organize your research

It’s easy to organize your research with our built-in tools.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

Monthly Plan

  • Read unlimited articles
  • Personalized recommendations
  • No expiration
  • Print 20 pages per month
  • 20% off on PDF purchases
  • Organize your research
  • Get updates on your journals and topic searches

$49/month

Start Free Trial

14-day Free Trial

Best Deal — 39% off

Annual Plan

  • All the features of the Professional Plan, but for 39% off!
  • Billed annually
  • No expiration
  • For the normal price of 10 articles elsewhere, you get one full year of unlimited access to articles.

$588

$360/year

billed annually
Start Free Trial

14-day Free Trial