Ramipril

Ramipril Reactions 1680, p293 - 2 Dec 2017 Hemi-angioedema: case report A 72-year-old woman developed hemi-angioedema during treatment with ramipril. The woman, who had been taking ramipril [indication, route and dosage not stated], presented with ’drooping of the left mouth angle’, which lasted for four hours [duration of treatment to reaction onset not stated]. Her neurological examination and brain CT scan were unremarkable. A subsequent cardiovascular test revealed atherosclerotic changes in the carotid bifurcations, with no significant stenosis. Three months later, the symptoms reappeared and subsided. Two months thereafter, she developed the same symptoms again, which included distinct swelling of the left lower lip, cheek and chin, without any facial weakness. It was noted that she had been taking ramipril for three years. Ramipril was discontinued and during three years of follow- up, she remained asymptomatic, without any recurrence of hemi-angioedema. Author comment: "Hemi-angioedema can be a rare side- effect associated with angiotensin-converting enzyme inhibitors, and symptoms can recur." Glibert N, et al. A transient ischemic attack mimic. Acta Neurologica Belgica 117: 919-920, No. 4, Dec 2017. Available from: URL: http://doi.org/10.1007/ s13760-017-0809-4 - Belgium 803284657 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Reactions Weekly Springer Journals

Ramipril

Reactions Weekly , Volume 1680 (1) – Dec 2, 2017
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Publisher
Springer International Publishing
Copyright
Copyright © 2017 by Springer International Publishing AG, part of Springer Nature
Subject
Medicine & Public Health; Drug Safety and Pharmacovigilance; Pharmacology/Toxicology
ISSN
0114-9954
eISSN
1179-2051
D.O.I.
10.1007/s40278-017-39224-5
Publisher site
See Article on Publisher Site

Abstract

Reactions 1680, p293 - 2 Dec 2017 Hemi-angioedema: case report A 72-year-old woman developed hemi-angioedema during treatment with ramipril. The woman, who had been taking ramipril [indication, route and dosage not stated], presented with ’drooping of the left mouth angle’, which lasted for four hours [duration of treatment to reaction onset not stated]. Her neurological examination and brain CT scan were unremarkable. A subsequent cardiovascular test revealed atherosclerotic changes in the carotid bifurcations, with no significant stenosis. Three months later, the symptoms reappeared and subsided. Two months thereafter, she developed the same symptoms again, which included distinct swelling of the left lower lip, cheek and chin, without any facial weakness. It was noted that she had been taking ramipril for three years. Ramipril was discontinued and during three years of follow- up, she remained asymptomatic, without any recurrence of hemi-angioedema. Author comment: "Hemi-angioedema can be a rare side- effect associated with angiotensin-converting enzyme inhibitors, and symptoms can recur." Glibert N, et al. A transient ischemic attack mimic. Acta Neurologica Belgica 117: 919-920, No. 4, Dec 2017. Available from: URL: http://doi.org/10.1007/ s13760-017-0809-4 - Belgium 803284657 0114-9954/17/1680-0001/$14.95 Adis © 2017 Springer International Publishing AG. All rights reserved Reactions 2 Dec 2017 No. 1680

Journal

Reactions WeeklySpringer Journals

Published: Dec 2, 2017

References

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