Radiotherapy for the treatment of thyroid eye disease—a prospective comparison: Is orbital radiotherapy a suitable alternative to steroids?

Radiotherapy for the treatment of thyroid eye disease—a prospective comparison: Is orbital... Ir J Med Sci (2017) 186:647–652 DOI 10.1007/s11845-016-1542-3 ORIGINAL ARTICLE Radiotherapy for the treatment of thyroid eye disease—a prospective comparison: Is orbital radiotherapy a suitable alternative to steroids? 1 1 2 3 1 • • • • P. Grassi D. Strianese R. Piscopo R. Pacelli G. Bonavolonta ` Received: 6 June 2016 / Accepted: 25 December 2016 / Published online: 3 January 2017 Royal Academy of Medicine in Ireland 2017 Abstract considered a suitable alternative treatment in TED for Background and aims To evaluate the efficacy of orbital patients who cannot tolerate steroids. radiotherapy (OR) for the treatment of thyroid eye disease (TED). Keywords Alternative first-line therapy  Graves Methods Thirty-five consecutive patients with active TED ophthalmopathy  Orbital radiotherapy  Thyroid eye with contraindications to steroid therapy received a course disease of OR. Bilateral retrobulbar irradiation was performed with a total dose of 20 Gy. 7-points clinical activity score (7- CAS), ocular motility, visual acuity (VA), exophthalmos Introduction and eyelid retraction were prospectively evaluated at 3, 6 and 12 months and compared with baseline data. Thyroid eye disease (TED) is an autoimmune disease Results There was a statistically significant improvement involving the retro-ocular and peri-ocular tissues associ- in http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Irish Journal of Medical Science (1971 -) Springer Journals

Radiotherapy for the treatment of thyroid eye disease—a prospective comparison: Is orbital radiotherapy a suitable alternative to steroids?

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Publisher
Springer London
Copyright
Copyright © 2017 by Royal Academy of Medicine in Ireland
Subject
Medicine & Public Health; Internal Medicine; General Practice / Family Medicine
ISSN
0021-1265
eISSN
1863-4362
D.O.I.
10.1007/s11845-016-1542-3
Publisher site
See Article on Publisher Site

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