Radiobiology and radiotherapy of brain metastases

Radiobiology and radiotherapy of brain metastases Brain metastases are the most common intracranial tumors in adults, accounting for more than 50% of all such cases. The approach to and management of brain metastases have evolved significantly in recent years due to several reasons. These include advances in neurosurgical and radiotherapeutic techniques, improved systemic therapy options offering better systemic and intracranial disease control and prolongation of survival as a result of these improvements, making side-effects of proposed therapies (e.g. neurocognitive decline from whole brain radiotherapy) an important consideration. In this article, we review the the primary therapeutic approaches to the management of brain metastases, namely, surgery, stereotactic radiosurgery, and whole brain radiation therapy and the primary factors dictating choice. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Clinical & Experimental Metastasis Springer Journals

Radiobiology and radiotherapy of brain metastases

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Publisher
Springer Netherlands
Copyright
Copyright © 2017 by Springer Science+Business Media B.V.
Subject
Biomedicine; Cancer Research; Biomedicine, general; Oncology; Hematology; Surgical Oncology
ISSN
0262-0898
eISSN
1573-7276
D.O.I.
10.1007/s10585-017-9865-7
Publisher site
See Article on Publisher Site

Abstract

Brain metastases are the most common intracranial tumors in adults, accounting for more than 50% of all such cases. The approach to and management of brain metastases have evolved significantly in recent years due to several reasons. These include advances in neurosurgical and radiotherapeutic techniques, improved systemic therapy options offering better systemic and intracranial disease control and prolongation of survival as a result of these improvements, making side-effects of proposed therapies (e.g. neurocognitive decline from whole brain radiotherapy) an important consideration. In this article, we review the the primary therapeutic approaches to the management of brain metastases, namely, surgery, stereotactic radiosurgery, and whole brain radiation therapy and the primary factors dictating choice.

Journal

Clinical & Experimental MetastasisSpringer Journals

Published: Nov 14, 2017

References

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