Radiation injury to cardiac arteries and myocardium is reduced by soy isoflavones

Radiation injury to cardiac arteries and myocardium is reduced by soy isoflavones Objective The negative effects of incidental radiation on the detected by 16 weeks after radiation. Soy isoflavones given heart and its vessels, particularly in the treatment of locally in conjunction with thoracic irradiation were found to reduce advanced non-small cell lung cancer, esophageal cancer, left- damage to the artery walls and radiation-induced fibrosis in sided breast cancer, and lymphoma, are known. Late cardiac the myocardium. events induced by radiotherapy including coronary artery dis- Conclusion Our histopathological findings suggest a radio- protective role of soy isoflavones to prevent cardiac injury. ease, ischemia, congestive heart failure, and myocardial in- farction can manifest months to years after radiotherapy. We This approach could translate to the use of soy isoflavones as a safe complement to thoracic radiotherapy with the goal have previously demonstrated that soy isoflavones mitigate inflammatory responses induced in lungs by thoracic irradia- of improving the overall survival in patients whose cancer has been successfully controlled by the radiotherapy but who oth- tion resulting in decreased vascular damage, inflammation, and fibrosis. In the current study, we investigate the use of erwise succumb to heart toxicity. soy isoflavones to protect cardiac vessels and myocardium . . . from radiation injury. Keywords Radiation http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Journal of Radiation Oncology Springer Journals

Radiation injury to cardiac arteries and myocardium is reduced by soy isoflavones

Loading next page...
 
/lp/springer_journal/radiation-injury-to-cardiac-arteries-and-myocardium-is-reduced-by-soy-gL60N7KB30
Publisher
Springer Journals
Copyright
Copyright © 2017 by Springer-Verlag Berlin Heidelberg
Subject
Medicine & Public Health; Oncology; Imaging / Radiology; Cancer Research; Surgical Oncology; Surgery; Radiotherapy
ISSN
1948-7894
eISSN
1948-7908
D.O.I.
10.1007/s13566-017-0301-z
Publisher site
See Article on Publisher Site

Abstract

Objective The negative effects of incidental radiation on the detected by 16 weeks after radiation. Soy isoflavones given heart and its vessels, particularly in the treatment of locally in conjunction with thoracic irradiation were found to reduce advanced non-small cell lung cancer, esophageal cancer, left- damage to the artery walls and radiation-induced fibrosis in sided breast cancer, and lymphoma, are known. Late cardiac the myocardium. events induced by radiotherapy including coronary artery dis- Conclusion Our histopathological findings suggest a radio- protective role of soy isoflavones to prevent cardiac injury. ease, ischemia, congestive heart failure, and myocardial in- farction can manifest months to years after radiotherapy. We This approach could translate to the use of soy isoflavones as a safe complement to thoracic radiotherapy with the goal have previously demonstrated that soy isoflavones mitigate inflammatory responses induced in lungs by thoracic irradia- of improving the overall survival in patients whose cancer has been successfully controlled by the radiotherapy but who oth- tion resulting in decreased vascular damage, inflammation, and fibrosis. In the current study, we investigate the use of erwise succumb to heart toxicity. soy isoflavones to protect cardiac vessels and myocardium . . . from radiation injury. Keywords Radiation

Journal

Journal of Radiation OncologySpringer Journals

Published: Mar 22, 2017

References

You’re reading a free preview. Subscribe to read the entire article.


DeepDyve is your
personal research library

It’s your single place to instantly
discover and read the research
that matters to you.

Enjoy affordable access to
over 18 million articles from more than
15,000 peer-reviewed journals.

All for just $49/month

Explore the DeepDyve Library

Search

Query the DeepDyve database, plus search all of PubMed and Google Scholar seamlessly

Organize

Save any article or search result from DeepDyve, PubMed, and Google Scholar... all in one place.

Access

Get unlimited, online access to over 18 million full-text articles from more than 15,000 scientific journals.

Your journals are on DeepDyve

Read from thousands of the leading scholarly journals from SpringerNature, Elsevier, Wiley-Blackwell, Oxford University Press and more.

All the latest content is available, no embargo periods.

See the journals in your area

DeepDyve

Freelancer

DeepDyve

Pro

Price

FREE

$49/month
$360/year

Save searches from
Google Scholar,
PubMed

Create lists to
organize your research

Export lists, citations

Read DeepDyve articles

Abstract access only

Unlimited access to over
18 million full-text articles

Print

20 pages / month

PDF Discount

20% off