Radiation-induced leiomyosarcoma following mastectomy: a case report

Radiation-induced leiomyosarcoma following mastectomy: a case report Adjuvant radiotherapy following mastectomy for breast carcinoma is the current standard of care; however, this has its own associated complications. One of the rare but documented long-term sequelae is the development of a radiation-induced soft tissue sarcoma. We present the case of a 76-year-old Caucasian female with a non-healing axillary ulcer several years post-radiotherapy for a right-sided breast carcinoma. She was referred to the plastic surgery unit for excision and reconstruction which involved a range of techniques including skin grafting and pedicled tissue transfer. Postoperative histology confirmed the rare diagnosis of radiation-induced leiomyosarcoma. This report describes the presentation, diagnosis and management options for a case of soft tissue sarcoma following radiotherapy. Although uncommon, this diagnosis should be considered in the presence of uncharacteristic skin changes after radiotherapy treatment. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png European Journal of Plastic Surgery Springer Journals

Radiation-induced leiomyosarcoma following mastectomy: a case report

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Copyright © 2010 by Springer-Verlag
Medicine & Public Health; Plastic Surgery
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  • Radiation-induced breast sarcoma
    Blanchard, DK
  • Radiation induced soft tissue sarcoma
    Davidson, T; Westbury, G; Harmer, CL

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