Rabovirus : a proposed new picornavirus genus that is phylogenetically basal to enteroviruses and sapeloviruses

Rabovirus : a proposed new picornavirus genus that is phylogenetically basal to enteroviruses and... We have sequenced the genome of a novel picornavirus, rabovirus A ( ra t- bo rne virus, RaBoV-A, NC_026314), which was present in the feces of a Norway rat ( Rattus norvegicus ) from Berlin, Germany. This virus is related to members of the genera Enterovirus and Sapelovirus . RaboV-A contains a type II IRES that is unlike the type I IRES elements of enteroviruses and the type IV elements of sapeloviruses. Its genome is marked by an L protein and a chymotrypsin-like 2A protease. Our analysis of g enome organization, pairwise i dentities, m otif, p hylogenic and U TR (GIMPU) indicates that RaBoV-A potentially represents a new picornavirus genus, for which we propose the name “ Rabovirus ”. Spread by their rodent hosts and detected in New York and Berlin rats, these viruses may have a wide geographic distribution. http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Archives of Virology Springer Journals

Rabovirus : a proposed new picornavirus genus that is phylogenetically basal to enteroviruses and sapeloviruses

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Springer Vienna
Copyright © 2015 by Springer-Verlag Wien
Biomedicine; Virology; Medical Microbiology; Infectious Diseases
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