RA: Klinik, Diagnostik und Outcome

RA: Klinik, Diagnostik und Outcome Update Rheumatologie ∙ RA: Klinik, Diagnostik und Outcome Keine erhöhte Malignomrate unter Biologika jahre). 287 dieser Patienten ent- Originalpublikation wickelten erstmals ein Melanom. Die standardisierten Inzidenzrati- Mercer LK, Askling J et al (2017) Risk of invasive melanoma in os (SIRs) waren für Biologika-nai- patients with rheumatoid arthritis ve Patienten 1,1 (95 %-CI 0,9–1,4), treated with biologics: results für TNF-Inhibitor-Behandelte 1,2 from a collaborative project of (0,99–1,6) und für Rituximab-ex- 11 European biologic registers. ponierte Patienten 1,3 (0,6–2,6). Ann Rheum Dis 76:386–391 Die Inzidenzrate verglichen mit Mercer LK, Galloway JB et al (2016) Biologika-naiven Patienten war Risk of lymphoma in patients exposed to antitumour necrosis für TNF-Inhibitoren 1,1 (95 %-CI factor therapy: results from the 0,8–1,6), für Rituximab 1,2 (0,5– British Society for Rheumatology 2,9). Die Schlussfolgerung war, 9 Eine anti- Biologics Register for Rheumatoid TNF-Therapie dass diese große europäische Ko- Arthritis. Ann Rheum Dis. ist offenbar operation keinen Hinweis auf ein http://dx.doi.org/10.1136/ nicht mit einem annrheumdis-2016-209389 erhöhtes Melanomrisiko nach Tumorrisiko Behandlung mit TNF-Inhibito- assoziiert Eine Arbeitsgruppe um Mer- ren fand. cer und Askling untersuchte un- Eine Auswertung des Regis- ter Auswertung von 11 Biologi- ters der britischen Gesellschaft für Gruppe 30 Lymphome (154 pro sehr erleichternd, dass nach aktu- ka-Registern aus 9 http://www.deepdyve.com/assets/images/DeepDyve-Logo-lg.png Zeitschrift für Rheumatologie Springer Journals

RA: Klinik, Diagnostik und Outcome

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Springer Medizin
Copyright © 2017 by Springer Medizin Verlag GmbH
Medicine & Public Health; Internal Medicine; Rheumatology
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