Skeletal Radiol (2017) 46:1385–1395 DOI 10.1007/s00256-017-2706-6 SCIENTIFIC ARTICLE Quantitative contrast-enhanced CT attenuation evaluation of osseous metastases following chemotherapy 1 1 1 1 Connie Y. Chang & F. Joseph Simeone & Martin Torriani & Miriam A. Bredella Received: 3 March 2017 /Revised: 14 June 2017 /Accepted: 19 June 2017 /Published online: 30 June 2017 ISS 2017 Abstract (P = 0.02). ICC was almost perfect for average attenuation Purpose Osseous metastases often undergo an osteoblastic and substantial for maximum attenuation. healing response following chemotherapy. The purpose of Conclusion Quantitative assessment of osseous metastatic our study was to demonstrate the quantitative CT changes in disease using CT attenuation measurements demonstrated a attenuation of osseous metastases before and after statistically significant increase in attenuation more than chemotherapy. 12 months after initiation of chemotherapy. Materials and methods Our study was IRB approved and . . HIPAA compliant. Our cohort consisted of 86 consecutive Keywords Osseous metastases Chemotherapy Healing . . . cancer patients with contrast-enhanced CTs before and response CT Attenuation Cancer 14 ± 2 (12–25) months after initiation of chemotherapy (60 ± 11 years, 36 males, 50 females). The average and max- imum metastasis attenuations were measured in Hounsfield Introduction units (HU) by
Skeletal Radiology – Springer Journals
Published: Jun 30, 2017
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