Nucl Med Mol Imaging (2017) 51:227–232 DOI 10.1007/s13139-017-0472-y ISSN (print) 1869-3482 ORIGINAL ARTICLE ISSN (online) 1869-3474 Quantification of Contraction Synchronicity and Contraction Work in Coronary Artery Disease 1 2 3 Takanaga Niimi & Mamoru Nanasato & Hisatoshi Maeda Received: 20 April 2016 /Revised: 28 December 2016 /Accepted: 13 January 2017 /Published online: 2 February 2017 Korean Society of Nuclear Medicine 2017 Abstract (p < 0.005). Using receiver operating characteristic analysis, Purpose This study quantified the contraction synchronicity values for the area under the curve showing the performance (CS; with 100% representing full synchrony and −100% of CA, CS, CWand LVEF in the diagnosis of CAD were 0.81, dyssynchrony) and contraction work (CW, millijoules per cen- 0.86, 0.78, and 0.84, respectively. timeter squared; representing myocardial area) in patients with Conclusion Asynchrony shown using the QSFP is useful for reduced left ventricular ejection fraction (LVEF) associated CAD detection. with coronary artery disease (CAD). Methods CS, CW and LVEF in 104 subjects (54 CAD pa- Keywords Contraction amplitude Contraction . . tients and 50 control subjects without CAD) were measured synchronicity Contraction work Left ventricular ejection using rest electrocardiography-gated single-photon emission fraction Coronary artery disease computed tomography (ECG SPECT). Contraction amplitude (CA),
Nuclear Medicine and Molecular Imaging – Springer Journals
Published: Feb 2, 2017
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