Qual Life Res (2017) 26:2397–2408 DOI 10.1007/s11136-017-1597-2 Quality of life among perinatally HIV-affected and HIV- unaffected school-aged and adolescent Ugandan children: a multi- dimensional assessment of wellbeing in the post-HAART era 1 2 3 1,4 • • • • A. K. Nkwata S. K. Zalwango F. N. Kizza J. N. Sekandi 1 1 5,6 7 • • • J. Mutanga M. Zhang P. M. Musoke A. E. Ezeamama Accepted: 16 May 2017 / Published online: 22 May 2017 Springer International Publishing Switzerland 2017 Abstract general wellbeing (GWB), present functioning, and general Objective To examine quality of life (QOL) in perinatally cognitive functioning (CF). Multivariable linear regression HIV-infected (PHIV) or HIV-exposed uninfected (PHEU) models estimated HIV-related percent differences (b)in vs. healthy HIV-unexposed uninfected (HUU) children QOL scores and 95% conﬁdence intervals (CI). during school-age/adolescence. Findings Compared to HUU CQOLI deﬁcits ranged from Methods PHIV infection was diagnosed via DNA PCR. 6.5 to 9.2% (95% CI -15.4, -1.6), GWB deﬁcit ranged Current HIV status was conﬁrmed by HIV rapid diagnostic from 6.5 to 10.5% (95% CI -16.0, -1.3), MDV deﬁcit test. Three HIV groups were deﬁned: PHIV, PHEU, and ranged from 6.8 to 11.6% (95% CI -14.5, 0.9), and CF HUU.
Quality of Life Research – Springer Journals
Published: May 22, 2017
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